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Lomerizine Hydrochloride

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Identification
Molecular formula
C26H37ClN2O4
CAS number
101477-54-7
IUPAC name
N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-pentyl-pyrrolidine-2-carboxamide;hydrochloride
State
State

At room temperature, lomerizine hydrochloride is in a solid state, typically distributed in a powder form. It is stable under normal temperature and pressure conditions.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
533.09g/mol
Molar mass
533.0900g/mol
Density
1.2000g/cm3
Appearence
Lomerizine hydrochloride is typically found as a white to off-white crystalline powder. It is not highly soluble in water but can dissolve in organic solvents such as ethanol.
Comment on solubility

Solubility of N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-pentyl-pyrrolidine-2-carboxamide; hydrochloride

Understanding the solubility of complex compounds like N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-pentyl-pyrrolidine-2-carboxamide; hydrochloride is essential for various applications, particularly in pharmaceuticals. The solubility of this compound can be influenced by several factors:

  • Solvent Polarity: This compound contains both hydrophobic and hydrophilic parts, suggesting it may have varying solubility in different solvents. Polar solvents may enhance solubility due to interactions with the hydroxyl groups.
  • pH Levels: As a hydrochloride salt, its solubility may increase in acidic conditions, which can also affect its ionization state.
  • Temperature: Generally, an increase in temperature may lead to higher solubility for solids; however, the precise relationship depends on the compound's specific characteristics.

In practical terms, “an understanding of solubility is pivotal for effective delivery and therapeutic outcomes”. For **N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-pentyl-pyrrolidine-2-carboxamide; hydrochloride**, conducting detailed solubility studies under various conditions would be critical in determining its optimal form for use. Depending on the intended application, one might explore the use of solubilizing agents to enhance its solubility for better performance in biological systems.

In conclusion, knowing the solubility characteristics can aid in the formulation of effective drugs, ensuring appropriate concentration levels are achieved in therapeutic settings.

Interesting facts

Interesting Facts about N-[2-chloro-1-(3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl)propyl]-4-pentyl-pyrrolidine-2-carboxamide; hydrochloride

This fascinating compound belongs to a class of chemicals known for their diverse biological activities and potential therapeutic applications. Here are some intriguing aspects of this particular compound:

  • Structural Complexity: The compound features a unique molecular structure with multiple functional groups, making it a subject of interest for medicinal chemistry and drug development.
  • Biological Relevance: Compounds with similar structures have been studied for their ability to modulate biological pathways, which may lead to important advances in pharmacology.
  • Potential Therapeutic Applications: Research suggests that compounds like this one may demonstrate beneficial effects in treating various diseases, particularly in areas like cancer, metabolic disorders, and infectious diseases.
  • Chirality Consideration: The presence of chiral centers within the compound means that different stereoisomers may exhibit different biological activities, making stereochemistry a critical factor in drug design.
  • Chlorine Atom: The inclusion of a chlorine atom in the structure is significant; halogenation often improves the pharmacokinetic properties of organic compounds and enhances their biological activities.
  • Hydrochloride Salt Formation: The hydrochloride form of this compound is likely used to improve its solubility and stability, which are critical attributes for pharmaceutical compounds.

In summary, the compound is not only structurally intriguing but also holds potential promise in the realm of medicinal chemistry. The multifaceted nature of its structure provides ample opportunities for research and development, contributing to the ever-evolving landscape of drug discovery.

Synonyms
AKOS040747168