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Carmustine

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Identification
Molecular formula
C5H11ClN2O2
CAS number
154-93-8
IUPAC name
N-(2-chloroethyl)-N-methyl-nitrous amide
State
State

Carmustine is generally found as a solid at room temperature.

Melting point (Celsius)
30.50
Melting point (Kelvin)
303.65
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
214.61g/mol
Molar mass
214.0560g/mol
Density
1.5400g/cm3
Appearence

Carmustine appears as an orange-yellow, crystalline powder. It is hygroscopic and typically administered in a formulation suitable for intravenous injection.

Comment on solubility

Solubility of N-(2-chloroethyl)-N-methyl-nitrous amide

N-(2-chloroethyl)-N-methyl-nitrous amide exhibits specific solubility characteristics that are noteworthy for various applications. Understanding its solubility is crucial for both laboratory and industrial processes.

Key Solubility Insights

  • Solvent Compatibility: This compound is generally soluble in organic solvents such as DMSO (dimethyl sulfoxide) and ethanol. However, it shows limited to no solubility in water, which is consistent with many nitrogen-containing organic compounds.
  • Temperature Dependency: The solubility can vary with temperature; typically, increasing temperature enhances solubility in organic solvents.
  • pH Influence: The solubility may also be affected by the pH of the solvent environment, as ionization can play a role in how the compound interacts with the solvent.
  • Practical Applications: Solubility in organic solvents makes it suitable for use in chemical reactions where aqueous conditions are not favorable.

It is important to note that the solubility of N-(2-chloroethyl)-N-methyl-nitrous amide reinforces its utility in organic synthesis and further research, but handling and storage should be conducted with care due to its chemical properties.

Interesting facts

Interesting Facts about N-(2-chloroethyl)-N-methyl-nitrous amide

N-(2-chloroethyl)-N-methyl-nitrous amide is a fascinating compound with a unique structure and a host of interesting applications. Here are some noteworthy aspects:

  • Historical Significance: This compound is part of a larger class of nitrous amides, which have been studied extensively for their potential pharmacological properties.
  • Chemical Behavior: N-(2-chloroethyl)-N-methyl-nitrous amide is known for its reactivity due to the presence of the nitrous amide group, making it a subject of interest for researchers looking to explore new synthetic pathways.
  • Biomedical Applications: The compound has been investigated for its potential in various therapeutic areas, including cancer treatment and as a potential neuroprotective agent due to its ability to modulate biological pathways.
  • Environmental Considerations: As a chlorinated compound, it raises questions regarding environmental impact and degradation. This adds another layer of complexity to its analysis and usage.
  • Research Opportunities: Due to its intriguing structure, N-(2-chloroethyl)-N-methyl-nitrous amide offers numerous research opportunities in the fields of medicinal chemistry and materials science. Exploring its versatility could lead to the development of novel therapeutic agents or innovative chemical materials.

In summary, N-(2-chloroethyl)-N-methyl-nitrous amide is not just an ordinary compound; it is a gateway to understanding complex chemical interactions and their potential applications in science and industry. As one researcher aptly stated, “Every compound tells a story, and it's our job to listen.”

Synonyms
N-Nitrosomethyl-2-chloroethylamine
(2-CHLOROETHYL)(METHYL)NITROSOAMINE
Methyl2chloraethylnitrosamin
Methyl(2chloroethyl)nitrosamine
2ChloroNmethylNnitrosoethanamine
2ChloroNmethylNnitrosoethylamine
Ethanamine, 2chloroNmethylNnitroso
Ethylamine, 2chloroNmethylNnitroso
Ethanamine, 2chloroNmethylNnitroso (9CI)
863-787-7
16339-16-5
N-(2-chloroethyl)-N-methylnitrous amide
2-Chloro-N-methyl-N-nitrosoethylamine
Methyl-2-chloraethylnitrosamin
Ethanamine, 2-chloro-N-methyl-N-nitroso-
2-Chloro-N-methyl-N-nitrosoethanamine
ETHYLAMINE, 2-CHLORO-N-METHYL-N-NITROSO-
Methyl-2-chloroethylnitrosamine
NSC-3370
Methyl(2-chloroethyl)nitrosamine
NSC 3370
BRN 1749600
Methyl-2-chloraethylnitrosamin [German]
N-Nitroso-N-methyl-2-chloroethylamine
6MZP8CY7TY
Ethanamine, 2-chloro-N-methyl-N-nitroso- (9CI)
WLN: ONN1&2G
CHEMBL167516
DTXSID50167576
NSC3370
JTJQWOJKHHOSMK-UHFFFAOYSA-N
AKOS006280170
1-(2-Chloroethyl)-1-methyl-2-oxohydrazine #
EN300-7577102