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N-(2-chlorophenyl)benzamide

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Identification
Molecular formula
C13H10ClNO
CAS number
2440-06-8
IUPAC name
N-(2-chlorophenyl)benzamide
State
State

At room temperature, N-(2-chlorophenyl)benzamide is typically in a solid state, specifically a crystalline form.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
353.50
Boiling point (Kelvin)
626.65
General information
Molecular weight
233.68g/mol
Molar mass
233.6770g/mol
Density
1.3392g/cm3
Appearence

N-(2-chlorophenyl)benzamide usually presents as a white to off-white crystalline powder. Its appearance can vary slightly depending on the purity and specific form it is obtained in.

Comment on solubility

Solubility of N-(2-chlorophenyl)benzamide

N-(2-chlorophenyl)benzamide, with the chemical formula C13H10ClN, displays interesting solubility characteristics that are influenced by its molecular structure.

Generally, this compound is known to be:

  • Moderately soluble in organic solvents such as ethanol and methanol.
  • Poorly soluble in water due to the hydrophobic nature of the aromatic rings.

The solubility behavior of N-(2-chlorophenyl)benzamide can be affected by several factors:

  • Temperature: Increased temperature often enhances solubility in various solvents.
  • Solvent Polarity: The choice of solvent significantly impacts solubility; non-polar solvents may provide better solubility compared to polar ones.
  • Functional Groups: The presence of the amide functional group can engage in hydrogen bonding, potentially increasing solubility in polar solvents slightly more than typical aromatic compounds.

In summary, while N-(2-chlorophenyl)benzamide is not readily soluble in water, it finds a better solubility profile in various organic solvents, which can be advantageous for specific applications in chemical synthesis and pharmaceutical formulations.

Interesting facts

Interesting Facts about N-(2-chlorophenyl)benzamide

N-(2-chlorophenyl)benzamide, often abbreviated as 2-CCB, is a fascinating compound that plays a significant role in the realm of organic chemistry. Here are some intriguing facts about this chemical:

  • Structural Insights: This compound features an amide functional group attached to a benzene ring, which contributes to its unique chemical properties. The presence of the 2-chlorophenyl group enhances the reactivity of the amide.
  • Medicinal Relevance: N-(2-chlorophenyl)benzamide and its derivatives have been investigated for their potential therapeutic applications. They may exhibit antimicrobial and anti-inflammatory properties, making them of interest in pharmaceutical research.
  • Versatile Synthesis: The synthesis of N-(2-chlorophenyl)benzamide can be achieved through various chemical pathways, including acylation reactions. This versatility allows chemists to modify the compound for different research purposes.
  • Research Applications: This compound is commonly used as a reference standard in analytical chemistry and can be utilized in studies involving chromatography and other separation techniques.
  • Potential as a Target Compound: Researchers are actively studying N-(2-chlorophenyl)benzamide for its possible role in the design of new materials and organic semiconductors, exploring how its properties can be harnessed in innovative technologies.

In conclusion, N-(2-chlorophenyl)benzamide is more than just a chemical structure; it represents the intersection of research and potential real-world applications. As science continues to evolve, compounds like 2-CCB are critical in paving the way for advancements in several fields.

Synonyms
N-(2-Chlorophenyl)benzamide
Benzamide, N-(2-chlorophenyl)-
NSC 406274
BRN 2105484
AI3-01073
DTXSID10144520
4-12-00-01122 (Beilstein Handbook Reference)
DTXCID9067011
qxzrwusaqskagt-uhfffaoysa-n
1020-39-9
2'-Chlorobenzanilide
Benzanilide, 2'-chloro-
N-(2-CHLOROPHENYL)-BENZAMIDE
Benzamide, N-(chlorophenyl)-
NSC406274
WLN: GR BMVR
MLS000679001
F0777-0979
IFLab1_003470
SCHEMBL3794850
CHEMBL1529752
HMS1421N16
HMS2710D10
MFCD00040850
STK325492
AKOS001604676
NSC-406274
NCGC00246610-01
FC137450
SMR000323401
CS-0329843
EU-0069674
F97441
SR-01000414623
SR-01000414623-1