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Lobeglitazone

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Identification
Molecular formula
C24H32Cl2N2
CAS number
857690-78-7
IUPAC name
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine
State
State

At room temperature, Lobeglitazone is in a solid state. This characteristic is essential for its use in pharmaceutical preparations where precise dosing is vital.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
425.82g/mol
Molar mass
425.8220g/mol
Density
1.2000g/cm3
Appearence

Lobeglitazone is typically a white to off-white powder. Its crystalline form enables it to be processed into a variety of pharmaceutical formulations.

Comment on solubility

Solubility of N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine

The solubility of N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine can be influenced by various factors, including its chemical structure and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of polar functional groups may enhance solubility in polar solvents, while non-polar regions might favor solubility in non-polar solvents.
  • Hydrogen bonding: If the compound can engage in hydrogen bonding, it tends to have increased solubility in water and other hydrogen-bonding solvents.
  • Temperature effects: Generally, solubility can vary with temperature; higher temperatures often lead to greater solubility.
  • pH dependence: Solubility may also depend on the pH of the solution, particularly if the compound contains acidic or basic groups that ionize.

In practical terms, for effective applications, one might often say: "The key to understanding solubility is recognizing the balance between hydrophilic and hydrophobic interactions." Therefore, determining the specific solubility characteristics of this compound requires cautious experimentation with various solvents and conditions.

Interesting facts

Interesting Facts about N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine

N-[(2-chlorophenyl)methyl]-1-[4-[[[2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine, commonly referred to in scientific circles for its complex structure, presents fascinating insights into its chemical behavior and potential applications.

Chemical Structure

This compound showcases a multifaceted architecture characterized by:

  • A chlorophenyl group that is pivotal in enhancing the compound's reactivity.
  • A cyclohexyl moiety, which contributes to its unique three-dimensional shape.
  • A secondary amine functionality that is critical for its interactions with biological systems.

Biological Relevance

Research has indicated that compounds with similar structural characteristics may exhibit:

  • Pharmacological Properties: Such structures have been investigated for potentials related to analgesia and anti-inflammatory effects.
  • Neurotransmitter Modulation: Compounds in this class can interact with various neurotransmitter receptors, hinting at possibilities within psychiatric applications.

Potential Applications

The intricacies of this compound's design suggest various fields of application:

  • In medicinal chemistry, it could serve as a lead molecule in drug discovery efforts.
  • In studies focusing on the synthesis of novel compounds, it may inspire the development of therapeutically beneficial agents.

Conclusion

As a rich subject of study, N-[(2-chlorophenyl)methyl]-1-[4-[[[2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine reflects how intricate molecular structures can pave the way for groundbreaking discoveries in chemistry and pharmacology. Its properties and potential applications underscore the importance of continual research in understanding complex chemical compounds.

Synonyms
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine
NSC123019
AY 9944 (*Dihydrochloride*)
N,N'-(Cyclohexane-1,4-diylbis(methylene))bis(1-(2-chlorophenyl)methanamine)
N,N'-[Cyclohexane-1,4-diylbis(methylene)]bis[1-(2-chlorophenyl)methanamine]
Tocris-1639
SCHEMBL7614548
SCHEMBL7614558
CHEMBL1513392
CHEMBL2062162
CHEBI:92062
AY-9944 (*Dihydrochloride*)
DTXSID50862610
NCGC00025242-01
NCGC00378548-01
trans 1,4-Bis(2-dichlorobenzylaminoethyl)cyclohexane
trans-1,4-bis(2-chlorobenzylaminomethyl)cyclohexane
BRD-K03642198-300-01-7
BRD-K77012840-300-01-6
Q27163857
1,4-Cyclohexanedimethanamine, N,N'-bis[(2-chlorophenyl)methyl]-, trans-
Trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine)
1-(2-chlorophenyl)-N-[[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methyl]methanamine
Trans-N,N-bis[2-Chlorophenylmethyl]-1,4-cyclohexanedime thanamine dihydrochloride
1170-60-1
1771-79-5