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Deschloroketamine Hydrochloride

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Identification
Molecular formula
C21H30Cl2N2
CAS number
1346599-08-9
IUPAC name
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine;dihydrochloride
State
State

At room temperature, Deschloroketamine Hydrochloride is typically found in a solid state as a crystalline powder. It is stable under standard conditions and should be stored in a dry place.

Melting point (Celsius)
186.00
Melting point (Kelvin)
459.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
318.23g/mol
Molar mass
318.2280g/mol
Density
1.2500g/cm3
Appearence

Deschloroketamine Hydrochloride, commonly referred to as 2-Cl-2'-Oxo-PCP, appears as a white or off-white crystalline powder. It is generally soluble in water, forming a clear solution.

Comment on solubility

Solubility of N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine;dihydrochloride

The solubility characteristics of this compound are influenced by its molecular structure and the presence of functional groups. As a dihydrochloride salt, it typically has improved solubility in aqueous environments compared to its free base form. Here are some key points regarding its solubility:

  • Aqueous solubility: The dihydrochloride form is generally soluble in water due to the ionic nature of the salt, which facilitates dissociation and hydration in polar solvents.
  • Organic solvent solubility: Depending on the specific structural features, such as the presence of hydrophobic chlorophenyl groups, the compound may exhibit variable solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • pH dependence: Solubility can also be affected by pH levels; an increase in acidity may promote dissolution of the compound, making it more soluble at lower pH.
  • Temperature effects: Higher temperatures typically enhance solubility, which could be particularly relevant during synthesis or formulation.

In summary, the solubility profile of N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine;dihydrochloride can be considered favorable for various applications, particularly in pharmacological contexts, where solubility plays a critical role in bioavailability.

Interesting facts

Interesting Facts about N-[(2-chlorophenyl)methyl]-1-[4-[[[2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine; dihydrochloride

N-[(2-chlorophenyl)methyl]-1-[4-[[[2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine; dihydrochloride is a fascinating compound with significant pharmacological implications. Here are some key points that highlight its importance:

  • Pharmacological Relevance: This compound belongs to a class of substances that are often investigated for their potential therapeutic properties, particularly in the realm of analgesics and psychoactive substances.
  • Structural Complexity: The chemical structure exhibits a complex arrangement of groups, including a cyclohexyl ring and multiple chlorophenyl moieties that contribute to its unique reactivity and interaction with biological systems.
  • Potential in Research: Researchers are interested in exploring this compound for its potential in treating various psychiatric disorders due to its interaction with neurotransmitter systems.
  • Chirality: The compound may possess chiral centers, introducing the possibility of enantiomeric forms that could exhibit different biological activities, making stereochemistry a critical aspect of its study.
  • Safety & Efficacy: As with many compounds undergoing research, understanding the mechanisms of action and studying the safety profiles in preclinical and clinical environments remains a top priority.
  • Regulatory Status: It is important to consider the regulatory landscape surrounding compounds like this one, as they could be classified under controlled substances or require extensive testing before reaching the market.

In conclusion, N-[(2-chlorophenyl)methyl]-1-[4-[[[2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine; dihydrochloride stands as a testament to the continual exploration of chemical compounds that hold promise for novel treatments in medicine. As ongoing research unravels its potential, we look forward to understanding more about its pharmacological properties and efficacy.

Synonyms
AY 9944
366-93-8
AY 9944 dihydrochloride
AY-9944
1245-84-7
NSC 123019
1,4-Cyclohexanedimethanamine, N,N'-bis((2-chlorophenyl)methyl)-, dihydrochloride, trans-
trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane dihydrochloride
DTXSID10957874
1,4-Cyclohexanebis(methylamine), N,N'-bis(o-chlorobenzyl)-, dihydrochloride
trans 1,4-Bis(2-dichlorobenzylaminoethyl)cyclohexane dichlorhydrate [French]
trans-N,N'-(1,4-Cyclohexylenedimethylene)bis(2-chlorobenzylamine) dihydrochloride
trans-N,N'-Bis(2-chlorobenzyl)-1,4-cyclohexanebis(methylamine) dihydrochloride
Benzylamine, N,N'-(1,4-cyclohexylenedimethylene)bis(2-chloro-, dihydrochloride, (E)-
trans 1,4-Bis(2-dichlorobenzylaminoethyl)cyclohexane dichlorhydrate
AY9944
1,4-Cyclohexanebis(methylamine), N,N'-bis(2-chlorobenzyl)-, dihydrochloride, (E)-
1,4-Cyclohexanebis(methylamine), N,N'-bis(o-chlorobenzyl)-, dihydrochloride, trans-
1-(2-CHLOROPHENYL)-N-[[4-[(2-CHLOROPHENYL)METHYLAMINOMETHYL]CYCLOHEXYL]METHYL]METHANAMINE DIHYDROCHLORIDE
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine;dihydrochloride
1,1'-((1r,4r)-cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride
trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride
1-(2-chlorophenyl)-N-[[4-[(2-chlorophenyl)methylaminomethyl]cyclohexyl]methyl]methanamine dihydrochl
MFCD01734586
AY9944dihydrochloride
cis-N,N'-(1,4-Cyclohexylenedimethylene)bis(2-chlorobenzylamine) dihydrochloride
cis-N,N'-Bis(2-chlorobenzyl)-1,4-cyclohexanebis(methylamine) dihydrochloride
1,4-Cyclohexanebis(methylamine), N,N'-bis(2-chlorobenzyl)-, dihydrochloride, (Z)-
Benzylamine, N,N'-(1,4-cyclohexylenedimethylene)bis(2-chloro-, dihydrochloride, (Z)-
SCHEMBL7920921
SCHEMBL7920925
CHEMBL3775982
DTXSID50924843
DTXCID701436162
1,4-BIS(2-CHLOROBENZYLAMINOMETHYL)CYCLOHEXANE DIHYDROCHLORIDE
HB3543
AKOS024319336
AKOS024456718
DA-71174
MS-28542
HY-107420
CS-0028448
G13054
SR-01000597971
SR-01000597971-1
1,4-Cyclohexanebis(methylamine), N,N'-bis(o-chlorobenzyl)-, dihydrochloride, trans-(8CI)
Cis-1,1'-(cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride
[(2-CHLOROPHENYL)METHYL]({[(1R,4R)-4-({[(2-CHLOROPHENYL)METHYL]AMINO}METHYL)CYCLOHEXYL]METHYL})AMINE DIHYDROCHLORIDE
622-252-6
N,N'-[Cyclohexane-1,4-diylbis(methylene)]bis[1-(2-chlorophenyl)methanamine]--hydrogen chloride (1/2)