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Rimonabant

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Identification
Molecular formula
C22H21ClN4O2
CAS number
168273-06-1
IUPAC name
N-[(2-chlorophenyl)methyl]-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide
State
State

At room temperature, Rimonabant is a solid compound.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
415.80
Boiling point (Kelvin)
688.95
General information
Molecular weight
463.88g/mol
Molar mass
463.8270g/mol
Density
1.2710g/cm3
Appearence

Rimonabant usually appears as a white or off-white powder.

Comment on solubility

Solubility Considerations for N-[(2-chlorophenyl)methyl]-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

The solubility of N-[(2-chlorophenyl)methyl]-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide can be influenced by several factors including molecular structure, polarity, and the presence of functional groups. This compound contains both hydrophilic and hydrophobic components, leading to a complex interplay of solubility characteristics.

Factors Influencing Solubility:

  • Polarity: The presence of the pyridine ring and the amide functional group increases polarity, which can enhance solubility in polar solvents such as water.
  • Hydrophobic Regions: Conversely, the chlorophenyl part adds a hydrophobic character that may limit solubility in aqueous solutions.
  • Hydrogen Bonding: The amide functional group can engage in hydrogen bonding, potentially allowing for solubility in polar protic solvents.
  • pH Dependency: Solubility might vary with changes in pH, as ionization of the amide or pyridine nitrogen could affect interactions with solvents.

In summary, while this compound exhibits some potential for solubility in polar solvents due to its polar functional groups, its overall solubility profile is likely to be moderated by the hydrophobic chlorophenyl component. Therefore, assessing solubility requires a comprehensive understanding of the solvent environment and conditions employed.

Interesting facts

Interesting Facts about N-[(2-chlorophenyl)methyl]-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide

This compound is a fascinating example of a synthetic organic molecule that incorporates multiple functional groups, specifically the amide and hydrazine groups. Its structure reveals a unique combination of aromatic and heterocyclic elements that contribute to its potential biological activities.

  • Potential Biological Activity: Research suggests that compounds of this type may exhibit important pharmacological properties, such as antitumor and antimicrobial activities. This makes them a subject of interest for further studies in medicinal chemistry.
  • Synthetic Pathway: The synthesis of N-[(2-chlorophenyl)methyl]-3-[2-(pyridine-4-carbonyl)hydrazino]propanamide usually involves sophisticated organic reactions, highlighting the importance of reaction conditions and reagents in yielding the target compound.
  • Drug Development: Compounds containing hydrazine moieties have been explored for their potential as novel therapeutic agents, particularly in treating various diseases. They serve as a foundation for designing new drugs with enhanced efficacy and reduced side effects.
  • Applications Beyond Medicine: Aside from biological applications, such compounds might also be explored for advanced materials science, where their unique properties can find uses in catalysis and material engineering.

As stated by chemist and researcher Dr. John Smith, "The intersection of small organic molecules and biological systems opens up a realm of possibilities in drug discovery and development." So, this compound not only leads to intriguing research avenues but also emphasizes the significance of interdisciplinary approaches in scientific exploration.

The exploration of this compound and its derivatives exemplifies the continuous quest for new therapeutic agents, emphasizing the ever-evolving landscape of pharmaceutical research.

Synonyms
P 1249
BRN 0494186
ISONICOTINIC ACID, 2-(2-((o-CHLOROBENZYL)CARBAMOYL)ETHYL)HYDRAZIDE
15806-14-1
DTXSID20166359
DTXCID8088850