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Chlorphenamine

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Identification
Molecular formula
C10H15ClN2
CAS number
132-22-9
IUPAC name
N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine
State
State

Chlorphenamine, at room temperature, is a solid compound typically processed in the form of a crystalline powder.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
276.80
Boiling point (Kelvin)
549.95
General information
Molecular weight
200.70g/mol
Molar mass
200.7000g/mol
Density
1.1250g/cm3
Appearence

Chlorphenamine appears as white or slightly yellow crystalline powder. It is typically odorless or nearly so.

Comment on solubility

Solubility of N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine

The solubility of N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine is influenced by several factors that stem from its unique chemical structure. Generally, this compound exhibits variable solubility depending on the medium in which it is dissolved.

Factors Influencing Solubility:

  • Polarity: The presence of the polar amine groups (-NH2) can enhance solubility in polar solvents like water, while the chlorophenyl moiety adds hydrophobic characteristics that can limit solubility.
  • Temperature: Like many compounds, solubility may increase with temperature, making it more likely to dissolve in hot solvents.
  • pH Levels: Depending on the pH of the solution, the amine groups can become protonated, potentially increasing solubility in acidic conditions.

It is often observed that such organic amines show mixed solubility behavior. The phrase “like dissolves like” is a key principle here:

  • In polar environments: Expect improved solubility.
  • In nonpolar environments: Solubility may be considerably lower.

In summary, while N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine can exhibit reasonable solubility in certain solvents, its overall solubility profile is complex and can be significantly affected by external conditions such as temperature and pH.

Interesting facts

Interesting Facts About N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine

N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine is a fascinating compound that falls under the category of amino compounds, specifically aromatic amines. This compound presents interesting chemistries and applications.

Key Features

  • Aromatic Structure: The presence of the 2-chlorophenyl group contributes to the compound's unique properties, allowing it to participate in various chemical reactions.
  • Biological Relevance: Compounds like this one can serve as intermediates in the synthesis of pharmaceuticals, particularly in the development of drugs targeting neurological disorders due to their ability to cross the blood-brain barrier.
  • Versatile Functionality: The two amine groups facilitate a variety of reaction mechanisms, including nucleophilic substitutions and coupling reactions, making it a valuable building block in organic synthesis.

Applications

  • Pharmaceutical Industry: It can be utilized in synthesizing potential therapeutic agents.
  • Research Applications: Commonly used in chemical research for exploring reaction pathways and mechanisms due to its reactivity.

In conclusion, N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine is more than just a simple organic compound; it is a potential key player in the field of medicinal chemistry. Its combination of chlorinated aromatic and aliphatic functional groups enhances its reactivity and application scope. As one of the many compounds that bridge the gap between organic synthesis and therapeutic applications, it is a great example of how seemingly simple structures can lead to complex and essential outcomes in science.

Synonyms
6241-46-9
ETHYLENEDIAMINE, 2-(CHLOROBENZYL)-
2-Chlorobenzylethylenediamine
BRN 0639400
DTXSID70211469
4-12-00-02363 (Beilstein Handbook Reference)
DTXCID20133960
N-(2-CHLOROBENZYL)ETHANE-1,2-DIAMINE
N'-[(2-chlorophenyl)methyl]ethane-1,2-diamine
(2-aminoethyl)[(2-chlorophenyl)methyl]amine
N1-(2-Chlorobenzyl)ethane-1,2-diamine
N-(2-Chlorobenzyl)ethylenediamine
1,2-Ethanediamine, N-[(2-chlorophenyl)methyl]-
SCHEMBL4706607
WTGFJEQTHKHUID-UHFFFAOYSA-N
ALBB-012108
MFCD01726880
STL168671
AKOS000264680
LS-03770
N1-(2-Chloro-benzyl)-ethane-1,2-diamine
H29845