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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]-2-(3,4,5-trimethoxyphenoxy)acetamide
State
State

At room temperature, lidocaine is commonly found as a solid, particularly as a powder or crystal. When used in medical applications, it is often formulated into an aqueous solution.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.00
Boiling point (Celsius)
427.00
Boiling point (Kelvin)
700.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3360g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is typically a white to slightly yellow crystalline powder. It is odorless and has a slightly bitter taste. It tends to form clear, colorless solutions in water and is usually available in the form of a hydrochloride salt for medical use.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]-2-(3,4,5-trimethoxyphenoxy)acetamide

The solubility of N-[2-(diethylamino)ethyl]-2-(3,4,5-trimethoxyphenoxy)acetamide, often referred to as a complex organic compound, is influenced by its structural features and the functional groups present. In general, the solubility characteristics can be summarized as follows:

  • Solvent Polarity: Compounds similar to this often exhibit varying solubility in polar vs. non-polar solvents. The presence of multiple methoxy groups tends to enhance solubility in organic solvents.
  • Functional Group Impact: The diethylamino group typically increases solubility in aqueous solutions due to its basic nature, allowing for hydrogen bonding.
  • Hydrophobic Considerations: The large phenoxy group renders the compound more hydrophobic, which may decrease its solubility in water but favor solubility in less polar solvents.
  • Temperature Dependence: As with many organic compounds, solubility can be temperature dependent, often increasing with higher temperatures.

Overall, while this compound may show appreciable solubility in organic solvents like ethanol or dichloromethane, it may struggle to dissolve in water. As with all chemical compounds, it is essential to conduct specific solubility tests in various solvents to obtain accurate data.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]-2-(3,4,5-trimethoxyphenoxy)acetamide

N-[2-(diethylamino)ethyl]-2-(3,4,5-trimethoxyphenoxy)acetamide, often referred to as a complex organic compound, is noteworthy for its unique structure and potential applications. Here are some fascinating aspects:

  • Complex Composition: This compound features both an amino group and a phenoxy group, showcasing an intriguing blend of functional groups that may contribute to its biological activity.
  • Potential Therapeutic Applications: Due to its diethylamino moiety, this compound could exhibit significant pharmacological properties, particularly in the realm of neuroscience. Compounds with amino groups are often studied for their roles in neurotransmitter modulation.
  • Modular Synthesis: The synthesis of such compounds often encourages innovative methodologies in organic chemistry, as it involves a multi-step synthesis that can introduce various substituents and functional modifications.
  • Multi-Functional Efficacy: The presence of trimethoxyphenoxy components suggests potential antioxidant properties and enhancements in drug solubility, making it a candidate for further research in drug formulation.
  • Structure-Activity Relationship (SAR): This compound provides a unique opportunity for chemists to explore SAR, as slight modifications to its structure may yield insights into its effectiveness and specificity, helping to design more potent analogs.

In conclusion, N-[2-(diethylamino)ethyl]-2-(3,4,5-trimethoxyphenoxy)acetamide represents a fascinating area of study in medicinal chemistry. Its complex structure not only paves the way for significant scientific exploration but also underscores the importance of understanding the implications of molecular design in pharmacology and therapeutic solutions.