Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]-2-(4-ethoxyphenoxy)-N-(3-methoxyphenyl)acetamide
State
State

At room temperature, Lidocaine is generally in a solid state appearing as a crystalline powder. In medical settings, it can also be available in liquid form when used as an injectable or as a gel.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3360g/mol
Density
0.9940g/cm3
Appearence

Lidocaine commonly appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. The compound is often formulated into a variety of dosage forms including solutions, creams, and gels for medical and anesthetic use.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]-2-(4-ethoxyphenoxy)-N-(3-methoxyphenyl)acetamide

The solubility of N-[2-(diethylamino)ethyl]-2-(4-ethoxyphenoxy)-N-(3-methoxyphenyl)acetamide can be influenced by several factors, including its molecular structure and the presence of various functional groups. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of both hydrophobic (ethyl and phenoxy groups) and hydrophilic (amide connection) components in its structure suggests that the compound may show variable solubility in polar and non-polar solvents.
  • Solvent Interaction: It is likely to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) due to its non-polar characteristics, while having limited solubility in water.
  • Temperature Influence: Higher temperatures often enhance the solubility of organic compounds; thus, evaluating the solubility at different temperatures could yield valuable data.
  • pH Sensitivity: The solubility may also vary with the pH of the solution, as the amine groups can become protonated under acidic conditions, potentially increasing solubility in aqueous environments.

In essence, while specific solubility data may not be readily available, understanding the solubility of this compound involves considering its structural features and the solvent environment. As with many organic compounds, empirical testing is essential to determine its precise solubility characteristics.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]-2-(4-ethoxyphenoxy)-N-(3-methoxyphenyl)acetamide

N-[2-(diethylamino)ethyl]-2-(4-ethoxyphenoxy)-N-(3-methoxyphenyl)acetamide is a fascinating compound with unique properties and applications in the field of medicinal chemistry.

Key Characteristics:

  • Versatile Applications: This compound may play a vital role in drug formulation and development due to its intricate structure, which allows for potential interactions with various biological targets.
  • Biological Activity: Compounds similar to this one have been explored for their efficacy in treating conditions such as neuropathic pain, anxiety disorders, and other neuropsychiatric conditions.
  • Structural Complexity: The presence of diethylamino groups combined with aromatic rings highlights the compound's potential for high biological activity and selective receptor binding.

Research into the derivatives of such compounds has shown promise in enhancing pharmacological properties. In some studies, they have been noted for increased *lipophilicity*, which can influence their permeability and bioavailability.

As a student of chemistry, one might find it exciting to explore the mechanisms by which this compound interacts at the molecular level, perhaps investigating how modifications in the structure can lead to variations in effectiveness and safety profiles.

Potential Research Areas:

  • Medicinal Chemistry: Exploring novel analogs can lead to the discovery of better therapeutic agents.
  • Toxicology: Understanding the safety profile is crucial, especially with compounds that have similar structures to known pharmaceuticals.
  • Drug Design: Utilizing computer-aided drug design tools could facilitate the optimization of bioactivity.

In summary, N-[2-(diethylamino)ethyl]-2-(4-ethoxyphenoxy)-N-(3-methoxyphenyl)acetamide represents a promising area of study, bridging organic chemistry with real-world therapeutic applications. As research progresses, we may uncover new insights that could transform our approach to treating complex diseases.