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Lidocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide
State
State

At room temperature, lidocaine is a solid.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine typically appears as a white crystalline powder. It is soluble in water and has a slightly bitter taste.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide

N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide, with the molecular formula C14H22N2O2, exhibits intriguing solubility characteristics that can greatly influence its applications in various fields. Understanding the solubility of this compound is essential for optimal use.

Factors Influencing Solubility

  • Polarity: This compound has both polar and non-polar components, which can affect its solubility in different solvents.
  • Hydrophilic and Hydrophobic Characteristics: The presence of the diethylamino group suggests a degree of hydrophilicity, while the methoxyphenyl group provides hydrophobic character.
  • Temperature Effect: Solubility can increase with temperature, particularly in organic solvents.

Solubility Profiles

It is generally anticipated that:

  • The compound may exhibit good solubility in organic solvents such as ethanol or dichloromethane.
  • Limited solubility in water can be expected due to its overall hydrophobic features.

In conclusion, the solubility of N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide is influenced by its unique molecular structure, with the interplay between hydrophilic and hydrophobic interactions playing a crucial role in its behavior in different environments. Understanding these solubility traits is vital for researchers and practitioners using this compound in practical applications.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide

N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide, often referred to in research settings as an acetamide derivative, possesses a fascinating range of characteristics that make it noteworthy within the field of medicinal chemistry. Here are some intriguing aspects of this compound:

  • Diverse Applications: This compound is explored for various pharmacological properties, particularly its role in neurological and pain-related therapies. Researchers are enthusiastic about its potential as a modulator for certain receptor systems.
  • Structure-Activity Relationship (SAR): The structural design of N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide allows for investigation into its binding affinity and selectivity towards specific targets, crucial in drug design. Small changes in the structure can lead to significant variations in biological activity.
  • Synthetic Versatility: The synthesis of this compound involves a series of steps that highlight the versatility of organic chemistry techniques. The incorporation of the diethylamino group and the methoxyphenoxy moiety adds layers of complexity that can be manipulated for desired effects in medicinal chemistry.
  • Research Opportunities: The ongoing studies into this compound not only involve elucidating its mechanism of action but also expansion into new therapeutic areas, such as cancer treatment or anti-inflammatory applications, making it a hot topic for further exploration.
  • A Key Building Block: Due to its unique molecular characteristics, this compound serves as an interesting building block for synthesizing more complex pharmaceuticals. The functional groups present offer rich opportunities for further functionalization through various chemical reactions.

As the world of medicinal chemistry continues to evolve, compounds like N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide remain at the forefront of innovation, showcasing the intersection of creativity and science in developing new therapeutic solutions.

Synonyms
mefexamide
1227-61-8
Timodyne
Mefexadyne
Mephexamide
Mexephenamide
Mefaxadyne
Mefexamida
Mefesamide [DCIT]
Mefexamidum
Mefesamide
Mefexamide [USAN:INN]
Mefexamidum [INN-Latin]
Mefexamida [INN-Spanish]
N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide
ANP 297
Acetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)-
EINECS 214-963-1
BRN 2219009
U-25701A
84FP054Z2Q
MEFEXAMIDE [MI]
N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide
MEFEXAMIDE [INN]
MEFEXAMIDE [USAN]
NSC-757827
MEFEXAMIDE [WHO-DD]
2-(p-Methoxyphenoxy)-N-(2-(diethylamino)ethyl)acetamide
acetamide, n-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)-
DTXSID5048475
NSC 757827
ACETAMIDE, N-(2-(DIETHYLAMINO)ETHYL)-2-(p-METHOXYPHENOXY)-
Mefexamidum (INN-Latin)
Mefexamida (INN-Spanish)
mefaxamid
mefessamide
SMR000685798
CAS-3413-64-7
Mefexamid
UNII-84FP054Z2Q
Spectrum_001294
Mefexamide (USAN/INN)
Prestwick0_000215
Prestwick1_000215
Prestwick2_000215
Prestwick3_000215
Spectrum2_001399
Spectrum3_000926
Spectrum4_001025
Spectrum5_001578
BSPBio_000229
KBioGR_001549
KBioSS_001774
MLS000881185
MLS000881195
DivK1c_000745
SCHEMBL126334
SPBio_001418
SPBio_002150
BPBio1_000253
CHEMBL1368380
DTXCID1028449
CHEBI:92373
KBio1_000745
KBio2_001774
KBio2_004342
KBio2_006910
KBio3_001932
HUNIPYLVUPMFCZ-UHFFFAOYSA-N
NINDS_000745
HMS2964H22
ALBB-036239
HY-B0950
STK370566
AKOS001033969
IDI1_000745
NCGC00016626-01
NCGC00016626-02
AS-75629
DA-75396
SBI-0051639.P002
AB00053594
NS00010043
D04894
G78321
AB00053594_13
EN300-6492976
BRD-K20655524-003-04-7
BRD-K20655524-003-07-0
BRD-K20655524-003-12-0
Q15634065
Z31448891
214-963-1