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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]-2-hydroxy-2-phenyl-N-(4-phenylphenyl)acetamide
State
State

At room temperature, lidocaine is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3430g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white or slightly yellow, crystalline powder. It is odorless and slightly bitter to the taste. The powder is typically used in a finely graded form.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]-2-hydroxy-2-phenyl-N-(4-phenylphenyl)acetamide

The solubility of N-[2-(diethylamino)ethyl]-2-hydroxy-2-phenyl-N-(4-phenylphenyl)acetamide, a complex organic compound, can be influenced by several factors:

  • Polarity: The presence of the -OH group suggests that the compound may exhibit some degree of polarity, potentially enhancing its solubility in polar solvents like water.
  • Hydrophobic Interactions: The substantial aromatic and alkyl substitutions can lead to hydrophobic characteristics that favor solubility in non-polar solvents, such as chloroform or toluene.
  • Chain Length: The diethylamino moiety contributes to the overall flexibility and solubility profile of the compound, which might improve solubility compared to less substituted counterparts.
  • Temperature: Generally, increasing temperature enhances solubility, providing a more favorable environment for dissolution.
  • pH Levels: The solubility may vary with the pH of the solvent. Adjusting pH could lead to ionization of the amino group, affecting the overall solubility.

Overall, while N-[2-(diethylamino)ethyl]-2-hydroxy-2-phenyl-N-(4-phenylphenyl)acetamide may show appreciable solubility in certain solvents under specific conditions, predicting its solubility necessitates a detailed understanding of its molecular structure and interactions in various environmental settings.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]-2-hydroxy-2-phenyl-N-(4-phenylphenyl)acetamide

This fascinating compound, commonly referred to as a type of secondary amide, showcases a multitude of interesting characteristics and applications within the realm of chemistry. Here are some key insights:

  • Pharmacological Applications: This compound has been studied for its potential use in pharmacology. Its unique molecular structure allows it to interact with various biological targets, making it a candidate for developing new medications.
  • Amine Functionality: The presence of diethylamino groups highlights the compound's basicity, which contributes to its reactivity and application in various chemical reactions.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step processes, typically employing reactions such as acylation and alkylation, which are fundamental in organic chemistry.
  • Research Potential: Due to its complex structure, it has drawn attention in research environments focused on discovering new compounds with improved efficacy as therapeutic agents.
  • Structural Diversity: The incorporation of both hydroxy and phenyl groups creates a versatile compound that can lend itself to numerous modifications, enabling chemists to tailor its properties for specific applications.

In summary, N-[2-(diethylamino)ethyl]-2-hydroxy-2-phenyl-N-(4-phenylphenyl)acetamide is not just a chemical compound; it's a symbol of the intricate interplay of structure and function in organic chemistry. As stated by notable chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This compound embodies that philosophy through its multitude of potential uses and research avenues.

Synonyms
AGN-PC-0JKIT3
14054-35-4
DTXSID90274814