Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide
State
State

At room temperature, lidocaine is typically in a solid state as a crystalline powder. It is soluble in water and other solvents and is often used in solution form for medical and laboratory applications.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is a white to off-white crystalline powder. It is usually odorless and has a slightly bitter taste. The compound is typically used in a pure, powder form for pharmaceutical applications, and may be dissolved in solutions for various medical and laboratory uses.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide

N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide, more commonly referred to as a type of amide compound, presents interesting solubility characteristics due to its unique structure. The solubility of this compound can be influenced by various factors including its functional groups, polarity, and environmental conditions. Here are some key points regarding its solubility:

  • Polarity: This compound features both hydrophilic (water-attracting) and hydrophobic (water-repelling) groups, which can affect its overall solubility in different solvents.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents, such as ethanol or dimethyl sulfoxide (DMSO), compared to water due to the larger hydrophobic components of its structure.
  • Temperature Influence: Solubility typically increases with temperature, so heating may enhance the dissolution of this compound in suitable solvents.
  • pH Sensitivity: Changes in pH could also influence solubility, especially considering the presence of nitrogen atoms that can be protonated or deprotonated depending on the conditions.

In summary, the solubility of N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide is affected by its composite structure and the environment in which it is placed. Understanding these factors is crucial for practical applications and further studies involving this compound.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide

N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide is a fascinating compound, primarily recognized for its central role in medicinal chemistry. Here are some noteworthy aspects:

  • Pharmacological Significance: This compound belongs to a class of molecules that have been studied for their potential therapeutic applications, particularly in the realm of neuropharmacology.
  • Structure-Activity Relationship: The unique diethylamino group enhances its solubility and bioavailability, making it a valuable candidate for drug development.
  • Reactivity: The presence of a but-2-enamide structure suggests that it can participate in various chemical reactions, such as nucleophilic additions or cycloadditions, which can lead to the formation of diverse chemical species.
  • Biological Activity: Compounds of this nature often exhibit a range of biological activities, which can include anti-inflammatory, analgesic, or even neuroprotective effects, making them intriguing targets for research.
  • Analog Synthesis: Scientists are exploring synthetic analogs of this compound to improve efficacy and reduce side effects, showcasing the compound's potential as a template in drug design.

It's important to note that, as with many compounds in medicinal chemistry, understanding the detailed interactions at a molecular level helps researchers devise improved therapeutic strategies.
“The right structure can transform a good lead compound into a blockbuster drug.” This illustrates the ongoing journey chemists take, using compounds like N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)but-2-enamide as stepping stones to future medicines.

Synonyms
20682-53-5
DB-320699
N-[2-(diethylamino)ethyl ]-N-(2,6-dimethylphenyl )-2-butenamide