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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide
State
State

At room temperature, lidocaine is a solid although it is commonly used as a solution for medical purpose.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white to off-white, odorless, crystalline powder. It may also be available in a clear colorless to slightly yellow solution form when dissolved in a suitable solvent.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide

The solubility of N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide is an intriguing subject due to its molecular structure and the interactions it may undergo in various solvents. This compound is characterized by the presence of both hydrophilic and hydrophobic regions, which can influence its solubility properties.

Factors Affecting Solubility:

  • Polarity: The diethylamino group tends to exhibit polar characteristics, making the compound more soluble in polar solvents such as water.
  • Hydrophobic Interactions: The presence of the 2,6-dimethylphenyl moiety introduces hydrophobicity, which can reduce solubility in highly polar environments.
  • Temperature: Increasing temperatures generally enhance solubility for many organic compounds, potentially leading to higher solubility levels for this formamide derivative.

In summary, the solubility of N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide can be significantly influenced by its molecular structure, the polarity of the solvent used, and environmental factors like temperature. It is essential to consider these factors to understand how this compound behaves in various chemical contexts. As the saying goes, "Like dissolves like," making solvent choice crucial for optimizing solubility.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide

N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide, often referred to in the scientific community for its unique structural properties, is a compound that plays a significant role in the field of medicinal chemistry. Here are some intriguing highlights:

  • Pharmacological Potential: This compound exhibits properties that may contribute to its function as a potential pharmaceutical agent, especially in targeting specific receptors in biological systems.
  • Amide Functionality: The presence of the amide group (-CONH-) in its structure is crucial. Amides are known for their stability and versatility in various chemical reactions, making this compound an interesting subject of study.
  • Substituent Diversity: The diethylamino group attached to the ethyl chain enhances the compound's lipophilicity, which can influence its ability to penetrate cellular membranes, an important factor in drug design.
  • Research Applications: Compounds like this are frequently evaluated for their activity against various diseases, including cancers and neurodegenerative disorders.

As a notable example of structure-activity relationships, this compound allows chemists to explore how modifications in the chemical structure influence biological activity. Researchers continuously seek to understand how such modifications can lead to more effective and selective therapeutic agents.

The ongoing exploration of compounds like N-[2-(diethylamino)ethyl]-N-(2,6-dimethylphenyl)formamide demonstrates the creative and innovative spirit of modern chemistry, highlighting the connection between molecular structure and biological function.

Synonyms
SA 117
20682-52-4
BRN 2734997
FORMANILIDE, N-(2-(DIETHYLAMINO)ETHYL)-2',6'-DIMETHYL-
N-(2-(Diethylamino)ethyl)-2',6'-dimethylformanilide
DTXSID80174738
3-12-00-02465 (Beilstein Handbook Reference)
DTXCID2097229
RefChem:345707