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DEET

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Identification
Molecular formula
C12H17NO
CAS number
134-62-3
IUPAC name
N-[2-(diethylamino)ethyl]benzamide
State
State

DEET is typically in liquid state at room temperature.

Melting point (Celsius)
-45.00
Melting point (Kelvin)
228.15
Boiling point (Celsius)
288.00
Boiling point (Kelvin)
561.15
General information
Molecular weight
191.27g/mol
Molar mass
191.2730g/mol
Density
0.9980g/cm3
Appearence

DEET is generally a colorless to yellow liquid. It has a faint odor, often described as slightly sweet or aromatic.

Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]benzamide

N-[2-(diethylamino)ethyl]benzamide is a compound whose solubility can be influenced by several factors. Understanding its solubility characteristics is crucial for applications in pharmaceuticals and chemical synthesis.

Generally, the solubility of N-[2-(diethylamino)ethyl]benzamide in various solvents can be summarized as follows:

  • Polar Solvents: This compound tends to have moderate solubility in polar solvents such as water due to the presence of the amide functional group, which can engage in hydrogen bonding.
  • Non-Polar Solvents: It shows higher solubility in non-polar solvents like chloroform or hexane, which is attributed to the hydrocarbon chains of the diethylamino group.
  • Effect of Temperature: Like many organic compounds, the solubility may increase with temperature, making it essential to consider thermal conditions during dissolution.

In practical use, it is often observed that:

  • The solubility of N-[2-(diethylamino)ethyl]benzamide can be enhanced in solutions with added surfactants.
  • Concentration of the compound significantly impacts its solubility profile, allowing for various formulations in aqueous or organic mediums.

To summarize, the solubility of N-[2-(diethylamino)ethyl]benzamide is largely dependent on the solvent type and temperature. This insight can facilitate its utilization in diverse chemical processes and applications. As always, “knowing the solubility is key to unlocking the potential of any compound.”

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]benzamide

N-[2-(diethylamino)ethyl]benzamide, often referred to within scientific discussions for its intriguing properties and applications, belongs to a unique class of compounds known for their biological activity. This compound stands out in several aspects:

  • Pharmaceutical Relevance: Known for its utility in the pharmaceutical industry, N-[2-(diethylamino)ethyl]benzamide can play a role in the synthesis of various biologically active compounds. Its derivatives have been studied for potential therapeutic uses, including anxiolytics and analgesics.
  • Structure & Function: The presence of the diethylamino group introduces interesting steric and electronic effects, enhancing the lipophilicity of the molecule. This is crucial for its interaction with biological membranes, impacting its absorption and distribution.
  • Analytical Techniques: Scientists often utilize advanced analytical techniques, such as NMR and HPLC, to study the behavior of this compound in different environments. Understanding its reaction pathways is vital for optimizing its usefulness in drug development.
  • Research Opportunities: The compound attracts research interest due to its potential as a lead compound for developing new medications. Ongoing studies often focus on improving its efficacy and reducing side effects.
  • Safety and Handling: As with many amides, safety protocols must be adhered to when handling N-[2-(diethylamino)ethyl]benzamide. Proper laboratory practices ensure that researchers can work safely while unlocking the compound's full potential.

In conclusion, N-[2-(diethylamino)ethyl]benzamide is not just a compound of interest but a gateway to advancements in medicinal chemistry. As one researcher eloquently stated, "The exploration of chemical compounds opens doors to understanding life at a molecular level." Its journey from laboratory synthesis to potential therapeutic applications encapsulates the dynamic nature of chemical science.

Synonyms
Bencainamide
N-(2-(Diethylamino)ethyl)benzamide
3690-53-7
N-[2-(diethylamino)ethyl]benzamide
GC 30
NSC 28817
BRN 1959405
W 769034
BENZAMIDE, N-(2-(DIETHYLAMINO)ETHYL)-
DTXSID90190383
3-09-00-01210 (Beilstein Handbook Reference)
DTXCID00112874
N-(2-diethylaminoethyl)benzamide
SCHEMBL542239
CHEMBL3303401
N-(beta-diethylaminoethyl)benzamide
NSC28817
NSC-28817
AKOS002957454
benzene, [(2-diethylamino)ethyl]carbamoyl-
DS-011507