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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[2-(diethylamino)ethyl]pyridine-4-carboxamide
State
State
At room temperature, lidocaine is typically found as a solid, in the form of a crystalline powder. It can also be dissolved in water or alcohol to form a clear solution for medical or laboratory use.
Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence
Lidocaine is typically a white, crystalline powder. It may also be available in an aqueous solution or as a topical ointment.
Comment on solubility

Solubility of N-[2-(diethylamino)ethyl]pyridine-4-carboxamide

N-[2-(diethylamino)ethyl]pyridine-4-carboxamide is a fascinating compound with notable solubility characteristics. This compound's solubility can be influenced by several factors:

  • Polarity: Due to the presence of both pyridine and carboxamide functional groups, this compound demonstrates moderate polarity, which enhances its solubility in polar solvents.
  • Solvent Compatibility: It is typically soluble in water and ethanol, making it useful in various applications where these solvents are prevalent.
  • Temperature Effects: Like many organic compounds, its solubility may increase with temperature, allowing for greater dissolution rates in heated conditions.
  • pH Dependency: The solubility can also be affected by the pH of the solution, given the carboxamide group can exist in different ionization states, impacting solubility in aqueous environments.

In summary, the solubility of N-[2-(diethylamino)ethyl]pyridine-4-carboxamide reflects its unique chemical structure, enabling it to dissolve effectively in various solvents, particularly under varying environmental conditions. Understanding these solubility properties can significantly impact its practical applications in fields such as pharmaceuticals and organic synthesis.

Interesting facts

Interesting Facts about N-[2-(diethylamino)ethyl]pyridine-4-carboxamide

N-[2-(diethylamino)ethyl]pyridine-4-carboxamide is a fascinating chemical compound with a variety of applications in different fields. Here are some intriguing aspects of this compound:

  • Pharmaceutical Applications: This compound is a key player in pharmacology, often being explored as a potential drug due to its unique structural properties that facilitate binding to biological targets.
  • Structure and Function: The presence of the diethylamino group can significantly enhance its lipophilicity, which may play a crucial role in the compound's ability to cross biological membranes.
  • Synthesis: The synthesis of this compound can involve various methods, including alkylation reactions or modifications of existing pyridine derivatives, showcasing the versatility of organic synthesis.
  • Research Relevance: N-[2-(diethylamino)ethyl]pyridine-4-carboxamide continues to be a subject of interest in academic research, particularly for studies related to nervous system interactions and drug design.
  • Potential Therapeutic Uses: Due to its structural characteristics, it may be evaluated for potential use in treating conditions related to the central nervous system, emphasizing the ongoing pursuit of novel therapeutics.

As a compound that bridges various fields within chemistry and pharmacology, N-[2-(diethylamino)ethyl]pyridine-4-carboxamide embodies the essence of innovation in drug development. Its interesting structure and potential applications show how chemistry is at the forefront of medical advancements.

Synonyms
Novocamide
Ambonestyl
ISONICOTINAMIDE, N-(2-(DIETHYLAMINO)ETHYL)-
6011-13-8
N-(2-(Diethylamino)ethyl)isonicotinamide
MC 4112
BRN 0165968
2-Dietil-aminoetil-isonicotinamide
2-Dietil-aminoetil-isonicotinamide [Italian]
DTXSID30208855
4-22-00-00539 (Beilstein Handbook Reference)
4-Pyridinecarboxamide, N-(2-(diethylamino)ethyl)-
DTXCID80131346
4-Pyridinecarboxamide, N-(2-(diethylamino)ethyl)-(9CI)
N-[2-(DIETHYLAMINO)ETHYL]PYRIDINE-4-CARBOXAMIDE
AKOS016605708