Edoxaban | Solubility of Things

Identification

Molecular formula

C₂₄H₃₀N₂O₆

CAS number

480449-70-5

IUPAC name

N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide

State

At room temperature, Edoxaban is typically found as a solid.

Melting point (Celsius)

234.50

Melting point (Kelvin)

507.65

Boiling point (Celsius)

450.00

Boiling point (Kelvin)

723.15

General information

Molecular weight

548.07g/mol

Molar mass

548.0670g/mol

Density

1.3501g/cm³

Appearence

Edoxaban appears as a crystalline, white to off-white solid.

Comment on solubility

Solubility of N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide

The solubility of N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide is a fascinating aspect of its chemical properties. Generally, solubility can be influenced by several factors, including the structure of the molecule, temperature, and solvent used. Here are some important points to consider:

Polarity: The presence of functional groups such as hydroxyl and carboxamide can contribute to the molecule's polarity.
Solvent Compatibility: This compound may show varying degrees of solubility in polar solvents (like water) versus non-polar solvents (like hexane).
Temperature Effects: Increased temperatures can enhance solubility for many compounds, so it is essential to consider thermal conditions.
Intermolecular Interactions: Hydrogen bonding and Van der Waals forces can significantly impact how well the compound dissolves in a given medium.

As with many organic compounds, predicting the solubility behavior without experimental data can be challenging. Therefore, when assessing N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide, it is advisable to conduct practical solubility tests to determine its behavior in specific environments. Understanding solubility not only aids in practical applications but also enhances our knowledge of the compound's chemical interactions.

Interesting facts

Interesting Facts about N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide

N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide is a fascinating compound noteworthy for its structure and potential applications. Here are some key points:

Pharmacological Significance: This compound is part of a class of molecules known for their biological activities. Compounds like it may have applications in pharmacology, particularly in developing new drugs.
Structural Diversity: The unique chromene scaffold provides this compound with varied reactivity, suggesting that it could serve as a template for synthesizing other derivatives that might enhance its efficacy or reduce side effects.
Amphiphilicity: Due to the presence of both hydrophobic isobutyl groups and hydrophilic amine and hydroxyl groups, the compound may exhibit interesting interactions in biological systems, allowing it to function effectively in drug delivery mechanisms.
Hydrogen Bonding: The presence of a hydroxy group may facilitate strong hydrogen bonding with biological targets, enhancing its binding affinity, which is a critical aspect of drug design.
Potential Applications: This compound is being investigated for various applications including but not limited to anti-inflammatory, antiviral, and anticancer therapeutic roles.

As a chemistry student or enthusiast, it's exciting to explore how modifications to the structure of this compound could lead to enhanced biological activity. The exploration of compounds like N-[2-(diisobutylamino)ethyl]-2-hydroxy-4-oxo-chromene-3-carboxamide not only enriches our understanding of organic chemistry but also paves the way for innovative medical solutions.