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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide
State
State

At room temperature, Lidocaine is typically in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0300g/cm3
Appearence

Lidocaine typically appears as a white or slightly yellow crystalline powder. It is odorless and has a slightly bitter taste. The compound is relatively soluble in water and highly soluble in ethanol and chloroform.

Comment on solubility

Solubility of N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide

The solubility characteristics of N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide can be intriguing due to its complex molecular structure. Here are some key points to consider:

  • Polarity: Given the presence of multiple functional groups, such as the dimethylamino and acetamide moieties, its overall polarity plays a crucial role in determining solubility.
  • Solvent Compatibility: This compound may exhibit different solubility profiles in:
    • Polar solvents: It might dissolve better in water or alcohols due to potential hydrogen bonding.
    • Non-polar solvents: Also, its aromatic rings suggest reasonable solubility in organic solvents like chloroform or benzene.
  • Temperature Influence: Solubility typically increases with temperature, so exploring various conditions can yield interesting results.
  • pH Sensitivity: Variations in pH can impact its ionization, thus altering solubility rates in aqueous solutions.

In summary, the solubility of N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide is influenced by several factors, including molecular structure, solvent type, temperature, and pH. Understanding these elements can help in predicting its behavior in various environments, making it an interesting compound to study.

Interesting facts

Interesting Facts about N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide

N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide, often referred to in the scientific community by its abbreviated name, is a compound that holds significant importance in medicinal chemistry. Here are some fascinating insights regarding this compound:

  • Pharmacological Relevance: This compound is notable for its interactions with receptors in the body, making it a subject of interest for developing potential therapeutic agents.
  • Structure-Activity Relationship: The unique configuration of substituents on the phenyl and acetamide groups suggests that slight modifications could lead to variations in biological activity, demonstrating the importance of molecular architecture in drug design.
  • Dimethylamino Group: The presence of the dimethylamino functional group is known for its ability to increase solubility and enhance biological activity, showing how functional group choice is critical in the development process.
  • Potential Applications: Researchers speculate potential uses in areas such as pain management and mental health, which highlights the ongoing need for innovative compounds in pharmaceutical research.
  • Chemistry and Stability: The molecule's stability can be affected by environmental factors, making the study of its reactivity and shelf-life crucial for real-world applications.

Overall, N-[2-(dimethylamino)-1-methyl-ethyl]-N-(2,6-dimethylphenyl)-2-phenyl-acetamide embodies the complexities and nuances in the world of organic chemistry, particularly in the pursuit of novel treatments. As research progresses, the full potential of this compound may pave the way for discoveries that significantly impact healthcare.

Synonyms
SA 48
18109-65-4
BRN 2769742
N-(2-(Dimethylamino)-1-methylethyl)-2',6'-dimethyl-2-phenylacetanilide
ACETANILIDE, N-(2-(DIMETHYLAMINO)-1-METHYLETHYL)-2',6'-DIMETHYL-2-PHENYL-
N-[1-(dimethylamino)propan-2-yl]-N-(2,6-dimethylphenyl)-2-phenylacetamide
SCHEMBL29393053
DTXSID60939408