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Bumetanide

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Identification
Molecular formula
C17H20N2O5S
CAS number
28395-03-1
IUPAC name
N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide
State
State

At room temperature, Bumetanide is typically in a crystalline solid form.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
364.42g/mol
Molar mass
364.4200g/mol
Density
1.2000g/cm3
Appearence

Bumetanide is a white to off-white crystalline powder.

Comment on solubility

Solubility of N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide

N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide exhibits interesting solubility characteristics that can be influenced by various factors. Understanding its solubility is crucial for its applications in pharmaceuticals and other fields. Here are some key points to consider:

  • Polar vs. Nonpolar Solubility: Due to the presence of the 4-hydroxy group, this compound is likely to exhibit some degree of polar characteristics, potentially allowing it to dissolve in polar solvents.
  • Organic Solvent Compatibility: Given its organic structure, N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide may show good solubility in organic solvents such as ethanol and acetone.
  • Temperature Influence: The solubility may also vary with temperature; typically, increased temperatures can enhance the solubility of solid compounds.
  • pH Sensitivity: The solubility could be affected by the pH of the solution due to the hydroxy group, making it worthwhile to investigate its solubility at different pH levels.

In summary, the solubility of N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide presents a fascinating area of study, characterized by its interactions with solvents and environmental factors. Understanding these aspects can greatly enhance its application and efficacy in various domains.

Interesting facts

Interesting Facts about N-[2-Ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide

N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide is a fascinating compound in the realm of organic chemistry. It belongs to a class of compounds known for their diverse biological activities and has been the subject of numerous research studies. Here are some captivating facts about this particular compound:

  • Biological Interest: This compound has attracted attention for its potential pharmacological properties. Researchers are investigating its effects in various biological systems, aiming to unveil mechanisms that could lead to therapeutic applications.
  • Synthetic Pathways: The synthesis of N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide offers a rich opportunity for chemists. The compound can be synthesized through multi-step reactions involving amine and carbonyl chemistry, showcasing the ingenuity of synthetic organic chemistry.
  • Functional Groups: Featuring both amide and hydroxy functional groups, the molecule exhibits properties that could lead to unique reactivity under certain conditions. These functional groups often play critical roles in biological activity and solubility.
  • Structure-Activity Relationship (SAR): The presence of the 3-methoxyphenyl group in the structure might contribute to the compound's bioactivity. Such modifications can alter pharmacokinetics and dynamics, making SAR studies essential for understanding how structural changes impact activity.
  • Interdisciplinary Applications: Due to its structural complexity, this compound serves as a prime example of how interdisciplinary approaches—ranging from medicinal chemistry to pharmacology—can converge in the study of new pharmaceuticals.

In summary, N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-butanamide is not just a name on a worksheet; it represents a rich field of study, where the synthesis, properties, and applications weave together to form a tapestry of scientific inquiry. As research continues, it is exciting to think about how this compound might contribute to advancements in medicine and beyond.

Synonyms
EMBUTRAMIDE
Embutane
15687-14-6
Embutramid
Embutramida
Embutramidum
Butanamide, N-(2-ethyl-2-(3-methoxyphenyl)butyl)-4-hydroxy-
HOE 18 680
3P4TQG94T1
DTXSID7057654
N-[2-Ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxybutanamide
HOE-18680
HOE-18-680
DTXCID8031443
Butanamide, N-[2-ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxy-
N-(2-ethyl-2-(3-methoxyphenyl)butyl)-4-hydroxybutanamide
N-(2-(3-methoxyphenyl)-2-ethylbutyl-(1))-gamma-hydroxybutyramide
239-780-4
T-61
N-(.beta.,.beta.-Diethyl-m-methoxyphenethyl)-4-hydroxybutyramide
Embutramidum [INN-Latin]
Embutramida [INN-Spanish]
Embutramide [USAN:INN:BAN]
EINECS 239-780-4
HOE 18,680
UNII-3P4TQG94T1
Tributane
Embutane (TN)
N-(beta,beta-Diethyl-m-methoxyphenethyl)-4-hydroxybutyramide
EMBUTRAMIDE [INN]
Embutramide (USAN/INN)
EMBUTRAMIDE [USAN]
EMBUTRAMIDE [MART.]
SCHEMBL294224
DEA No. 2020
EMBUTRAMID [GREEN BOOK]
CHEMBL2104668
Tox21_113716
HY-U00009
CS-6631
DB01487
Embutramide 1.0 mg/ml in Acetonitrile
HOE-18 680
NCGC00253572-01
CAS-15687-14-6
NS00006548
D03984
Q908240
N-[2-Ethyl-2-(3-methoxyphenyl)butyl]-4-hydroxybutanamide #
N-(.beta.,.beta.-Dimethyl-m-methoxyphenethyl)-4-hydroxybutyramide