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N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine

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Identification
Molecular formula
C11H14N2O
CAS number
823192-42-5
IUPAC name
N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine
State
State

At room temperature, N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine is typically found in a solid state.

Melting point (Celsius)
89.50
Melting point (Kelvin)
362.65
Boiling point (Celsius)
317.20
Boiling point (Kelvin)
590.35
General information
Molecular weight
176.24g/mol
Molar mass
176.2370g/mol
Density
1.0860g/cm3
Appearence

This compound typically appears as a solid crystalline substance under standard conditions.

Comment on solubility

Solubility of N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine

N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine is a compound whose solubility can greatly depend on various factors, including the nature of the solvent and the temperature. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of polar and non-polar groups in the structure can influence the solubility in polar solvents like water versus non-polar solvents such as organic solvents.
  • Hydrogen Bonding: The amine group can potentially participate in hydrogen bonding, enhancing solubility in protic solvents.
  • Temperature Dependency: Solubility often increases with temperature; thus, evaluating this compound at varying temperatures may yield different solubility results.
  • pH Level: The solubility of amines is also affected by the pH of the solution. In acidic conditions, the amine can be protonated, which may increase its solubility in water.

In practice, it has been reported that N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine exhibits limited solubility in water, which is common for many organic compounds due to hydrophobic characteristics. However, it may dissolve better in organic solvents such as methanol or ethanol.

To sum up, determining the solubility of N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine requires careful consideration of these factors, and it would be wise to conduct detailed solubility tests for specific applications.

Interesting facts

Interesting Facts about N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine

N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine is a compelling compound with a variety of intriguing properties and potential applications in the field of chemistry. Below are some noteworthy points about this compound:

  • Structural Significance: The presence of the oxazole ring in its structure contributes to the compound's unique reactivity and biological activity, making it an interesting target for pharmaceutical research.

  • Biological Implications: Compounds featuring amine groups, like this one, often play crucial roles in medicinal chemistry. They can influence the pharmacokinetics and pharmacodynamics of drugs, affecting everything from absorption to interaction with biological targets.

  • Electronic Properties: The ethyl group attached to the phenyl ring can significantly influence the electron-donating or withdrawing properties of the compound. This can lead to variations in reactivity with other chemical species.

  • Potential Applications: Research indicates that derivatives of dihydrooxazoles might showcase activity in various biological systems, including antitumor and antimicrobial effects, revealing their importance in drug discovery.

  • Historical Context: Dihydrooxazole derivatives have been a subject of interest since the early 20th century, with ongoing studies exploring their roles in synthetic chemistry and biological systems.

In summary, N-(2-ethylphenyl)-4,5-dihydrooxazol-2-amine serves as a fascinating example of how structural elements can converge to yield compounds with significant potential in both research and application. As chemistry continues to evolve, compounds like this one remain at the forefront of exploration and discovery.

Synonyms
2-(o-Ethylanilino)-2-oxazoline
ANILINE, o-ETHYL-N-(2-OXAZOLIN-2-YL)-
2-Oxazoline, 2-(o-ethylanilino)-
2-(o-Ethylphenylamino)-2-oxazoline
23417-38-1
N-(2-Ethylphenyl)-4,5-dihydro-2-oxazolamine
2-Oxazolamine, N-(2-ethylphenyl)-4,5-dihydro-
DTXSID60177969
RefChem:319647
DTXCID70100460
2-Oxazolamine, N-(2-ethylphenyl)-4,5-dihydro-(9CI)
CHEMBL2285877