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N-(2-fluoroethyl)aniline

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Identification
Molecular formula
C8H10FN
CAS number
445-73-4
IUPAC name
N-(2-fluoroethyl)aniline
State
State

At room temperature, N-(2-fluoroethyl)aniline is typically a liquid.

Melting point (Celsius)
-8.00
Melting point (Kelvin)
265.15
Boiling point (Celsius)
190.00
Boiling point (Kelvin)
463.15
General information
Molecular weight
137.17g/mol
Molar mass
137.1680g/mol
Density
1.1020g/cm3
Appearence

N-(2-fluoroethyl)aniline appears as a colorless to pale yellow liquid. It is usually somewhat viscous and has a characteristic aromatic amine odor.

Comment on solubility

Solubility of N-(2-fluoroethyl)aniline

N-(2-fluoroethyl)aniline, a compound featuring both an amine and a fluoroalkyl group, exhibits interesting solubility characteristics. Its solubility can generally be influenced by the following factors:

  • Polarity: The presence of the amine group, which is polar, can enhance the compound's solubility in polar solvents like water.
  • Hydrophobicity: The fluoroethyl group can contribute to hydrophobic interactions, potentially reducing solubility in water but enhancing solubility in organic solvents.
  • Functional Group Compatibility: The non-polar characteristics of the fluoro group might make the compound more soluble in non-polar solvents, such as hexane or toluene.

Overall, N-(2-fluoroethyl)aniline is expected to have:

  • Moderate solubility in water, due to the polar amine function.
  • Good solubility in organic solvents, attributing to the hydrophobic nature imparted by the fluoroethyl group.

As such, understanding the solubility of N-(2-fluoroethyl)aniline can be critical for applications in chemical synthesis and material science, allowing researchers to select the appropriate solvents for reactions involving this unique compound.

Interesting facts

Interesting Facts about N-(2-fluoroethyl)aniline

N-(2-fluoroethyl)aniline is a fascinating compound that holds significant relevance in both industrial and academic settings. Here are some noteworthy points about this intriguing chemical:

  • Chemical Structure: This compound is characterized by the presence of an aniline group, which is an aromatic amine, connected to a 2-fluoroethyl chain. The presence of the fluorine atom introduces unique properties that can impact its chemical reactivity and stability.
  • Applications: N-(2-fluoroethyl)aniline is utilized in a variety of applications. It's often employed in the production of pharmaceutical intermediates, agrochemicals, and dyes. This versatility makes it an essential compound in synthetic organic chemistry.
  • Fluorine's Role: The incorporation of fluorine into organic compounds is a popular strategy to enhance their bioactivity or chemical stability. In the case of N-(2-fluoroethyl)aniline, the fluorine atom can influence its interaction with biological systems, potentially leading to interesting pharmacological properties.
  • Research Potential: The unique characteristics of fluorinated compounds have made them a focal point in current research. Many scientists are investigating N-(2-fluoroethyl)aniline due to its potential applications in medicinal chemistry and material science.
  • Safety Considerations: As with all chemical compounds, proper handling and safety protocols are crucial. Understanding its toxicity and environmental impact promotes safer laboratory practices and sustainable chemistry.

In summary, N-(2-fluoroethyl)aniline is an intriguing compound that continues to capture the interest of chemists due to its numerous applications and the significant influence that fluorine exerts on its chemical properties. It serves as a prime example of how modifications at the molecular level can lead to diverse functionalities and enhanced performance in various fields of science.

Synonyms
N-(2-fluoroethyl)aniline
459-40-5
(2-Fluoro-ethyl)phenyl-amine
SCHEMBL415411
(2-Fluoro-ethyl)-phenyl-amine
FTPHSZHORWIRPP-UHFFFAOYSA-N
AKOS006350937
CS-W023117
D77931