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N-(2-fluorophenyl)benzamide

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Identification
Molecular formula
C13H10FNO
CAS number
51610-54-1
IUPAC name
N-(2-fluorophenyl)benzamide
State
State
N-(2-fluorophenyl)benzamide is a solid at room temperature, typically appearing in a crystalline form.
Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
345.20
Boiling point (Kelvin)
618.35
General information
Molecular weight
215.22g/mol
Molar mass
215.2240g/mol
Density
1.2880g/cm3
Appearence

N-(2-fluorophenyl)benzamide generally appears as a white to off-white crystalline solid. Its purity and specific form (such as powder or crystals) may vary depending on the method of synthesis and any potential impurities.

Comment on solubility

Solubility of N-(2-fluorophenyl)benzamide

N-(2-fluorophenyl)benzamide is a compound with interesting solubility characteristics. Understanding its solubility behavior is essential for potential applications in various fields, especially pharmaceuticals and materials science.

This compound demonstrates the following solubility traits:

  • Solvent Compatibility: N-(2-fluorophenyl)benzamide is generally soluble in organic solvents such as ethanol, methanol, and dichloromethane.
  • Water Solubility: It exhibits low solubility in water, which is common for many amides of this nature, primarily due to their hydrophobic aromatic structures.
  • Temperature Influence: Like many organic compounds, the solubility can increase with temperature, indicating that heating may aid in dissolving the compound more effectively.

As a rule of thumb, "like dissolves like," meaning non-polar substances typically dissolve well in non-polar solvents, while polar substances are soluble in polar solvents. Thus, for N-(2-fluorophenyl)benzamide, its hydrophobic characteristics lead to greater affinity for organic solvents over water.

In summary, while N-(2-fluorophenyl)benzamide is soluble in a range of organic solvents, it shows limited solubility in aqueous environments, underscoring its utility and considerations in various chemical applications.

Interesting facts

Interesting Facts about N-(2-Fluorophenyl)benzamide

N-(2-Fluorophenyl)benzamide, a fascinating compound in the realm of synthetic organic chemistry, showcases several interesting attributes that are worthy of exploration. This compound, categorized as an amide, is notable for its unique structural configuration, which features a fluorine atom attached to a phenyl group. Here are some key points to consider:

  • Reactivity and Applications: The presence of the fluorine atom greatly influences the compound's reactivity. Fluorinated compounds often exhibit enhanced bioactivity, making N-(2-Fluorophenyl)benzamide an intriguing subject for medicinal chemistry and drug design.
  • Surfactant Properties: Amides like this compound can function as surfactants due to their dual hydrophilic and hydrophobic nature. This property can be exploited in various formulations, from pharmaceuticals to cosmetic applications.
  • Research Significance: As a fluorinated derivative, it plays a role in the study of molecular interactions and pharmacokinetics. Scientists are often interested in how such modifications impact biological activity.
  • Potential in Material Science: With ongoing research into novel material properties of fluorinated compounds, N-(2-Fluorophenyl)benzamide may present possibilities in polymeric materials or coatings.

In summary, N-(2-Fluorophenyl)benzamide is more than just a simple compound; it is a gateway to understanding broader principles of chemistry and its applications in various fields. As the famous chemist Linus Pauling once said, "Science is not only compatible with spirituality; it is a profound source of spirituality." The exploration of compounds like this brings us closer to unraveling the complexities of chemical interactions and their implications in real-world applications.

Synonyms
N-(2-fluorophenyl)benzamide
367-97-5
Benzanilide, 2-fluoro-
NSC51886
CBMicro_009304
2-FLUOROBENZANILIDE
Cambridge id 5136687
2'-FLUOROBENZANILIDE
AW7N5CVS37
SCHEMBL2113824
Benzamide, N-(2-fluorophenyl)-
CCG-710
DTXSID30957937
UZPGWRCSQTZJAB-UHFFFAOYSA-N
SMSF0003648
MFCD00086049
NSC 51889
NSC-51886
STK018903
AKOS002960471
CB12412
HS-3732
N-Benzoyl derivative of o-fluoroaniline
BIM-0009522.P001
N-(2-Fluorophenyl)benzenecarboximidic acid
F97438
AO-548/05797021