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Fluorobenzamide

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Identification
Molecular formula
C14H13FN2O3S
CAS number
635702-60-2
IUPAC name
N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide
State
State

At room temperature, Fluorobenzamide is a solid. It maintains a crystalline structure, which is common for organic compounds of similar molecular complexity.

Melting point (Celsius)
177.00
Melting point (Kelvin)
450.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
303.32g/mol
Molar mass
303.3160g/mol
Density
1.4000g/cm3
Appearence

Fluorobenzamide appears as a white to off-white crystalline solid. It is typically odorless and may exhibit a slightly bitter taste.

Comment on solubility

Solubility of N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide

The solubility of N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide (C14H13FN2O3S) can be characterized by several important factors:

  • Polarity: The presence of the sulfonamide functional group contributes to some degree of polarity, which influences its interaction with polar solvents.
  • Solvent Interaction: It is often more soluble in polar protic solvents (like water and alcohol) compared to nonpolar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water can enhance its solubility, particularly due to the sulfonamide group.

In general, solubility in liquid media is critical for the compound's application, especially in biological systems. An important observation is that:

  1. The behavior can vary significantly based on the solvent used.
  2. Room temperature solubility may differ from solubility at elevated temperatures.
  3. Stability in solution can affect the overall efficacy when used in formulations.

In summary, the solubility of N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide is influenced by its molecular structure, and understanding its solubility is essential for its practical applications. As the saying goes, "like dissolves like", highlighting the importance of matching the solvent properties with the compound's characteristics for optimal dissolution.

Interesting facts

Interesting Facts about N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide

N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide is a fascinating chemical compound that finds its relevance primarily in the field of medicinal chemistry. Here are some engaging insights:

  • Pharmaceutical Applications: This compound is often investigated for its potential use as a therapeutic agent. It belongs to a class of compounds known as sulfonamides, which have been recognized for their antibacterial properties.
  • Fluorine's Role: The presence of the fluorine atom in the structure enhances its metabolic stability and lipophilicity, which can significantly impact the compound's effectiveness in drug formulation.
  • Mechanism of Action: Compounds like N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide may exert their effects by inhibiting specific enzymes in bacterial pathways, thus disrupting critical biological processes vital for survival.
  • Structure-Activity Relationship (SAR): The specific arrangement of functional groups within this compound plays a crucial role in its biological activity. Researchers often focus on altering these groups to optimize efficacy and minimize side effects.
  • Analytical Techniques: Chemists utilize a wide range of analytical techniques, such as NMR and mass spectrometry, to elucidate the structure and stability of this compound, as well as to track its behavior in biological systems.

This chemical offers a noteworthy intersection between organic chemistry and pharmacology, showcasing how tailored molecular designs can lead to advancements in healthcare.

As you delve deeper into the world of medicinal agents, remember the importance of compounds like N-[(2-fluorophenyl)methyl]-4-sulfamoyl-benzamide that continue to shape our understanding of disease treatment and drug development. Research in this area remains a dynamic and critical pursuit for scientists worldwide.

Synonyms
n-(2-flouro-benzyl)-4-sulfamoyl-benzamide
N-[(2-fluorophenyl)methyl]-4-sulfamoylbenzamide
n-(2-fluoro-benzyl)-4-sulfamoyl-benzamide
N-((2-fluorophenyl)methyl)-4-sulfamoylbenzamide
2-fluoro-SBB
1g1d
SCHEMBL678599
BDBM12014
1g45
AKOS008607291
DB02069
PD008580
NS00069144
Q27093148
Z33640422
4-(AMINOSULFONYL)-N-[(2-FLUOROPHENYL)METHYL]-BENZAMIDE