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Ceramide 3

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Identification
Molecular formula
C34H67NO3
CAS number
100403-19-8
IUPAC name
N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide
State
State

At room temperature, Ceramide 3 is found in a solid state. This solid lipid can easily integrate into various formulations in cosmetic and dermatological applications due to its compatibility with other lipid substances.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
398.00
Boiling point (Kelvin)
671.15
General information
Molecular weight
563.93g/mol
Molar mass
563.0270g/mol
Density
0.9840g/cm3
Appearence

Ceramide 3 is typically a white or off-white, waxy solid. It can appear as a powder or in some cases as a pellet form. The compound is often described as having a slightly greasy or slick appearance due to its lipid nature.

Comment on solubility

Solubility of N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide

The compound N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide, with the chemical formula C34H67NO3, exhibits unique solubility characteristics that can be attributed to its large hydrocarbon chain and the presence of functional groups.

Factors Affecting Solubility

Several factors influence the solubility of this compound:

  • Hydrophobic Nature: The significant length of the hydrocarbon chain often results in a low solubility in polar solvents such as water.
  • Hydrophilic Functional Groups: The hydroxyl groups (–OH) can interact favorably with polar solvents which may enhance solubility to a degree.
  • Chain Length: Longer hydrocarbon chains tend to favor solubility in non-polar solvents, which suggests that this compound may be more soluble in organic solvents.

Predicted Solubility Outcomes

Based on these characteristics, we can predict the solubility outcomes of N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide:

  • Likely insoluble in water due to its hydrophobic nature.
  • Possibly soluble in various organic solvents such as ethanol or methanol, due to the presence of hydroxyl groups.
  • Utilization in Formulations: Its solubility profile makes it suitable for applications in cosmetic and pharmaceutical formulations where compatibility with oils may be required.

Overall, the solubility of N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide is influenced primarily by the balance between its hydrophobic hydrocarbon backbone and hydrophilic functional groups, creating an interesting interplay that defines its behavior in different solvent environments.

Interesting facts

Interesting Facts about N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide

This unique compound belongs to the class of fatty acids and amides, showcasing a fascinating blend of structural complexity and biological significance. Here are some of the most intriguing aspects:

  • Biological Role: This compound plays a crucial role in the synthesis of sphingolipids, which are vital components of cell membranes.
  • Potential Therapeutic Applications: Due to its structural similarity to certain signaling molecules, it is being explored for its potential anti-inflammatory properties.
  • Natural Origin: This compound can be derived from natural sources, particularly in plant-based systems, emphasizing its prominence in biodiverse environments.

Moreover, the compound's structure includes both hydroxyl groups and long hydrocarbon chains, which can contribute to its solubility characteristics and interaction with biological membranes. As a result, it may influence cellular signaling pathways and lipid metabolism.

"The intricate details of molecular interactions often hold the key to unlocking new therapeutic insights." This particular compound exemplifies such complexity, revealing the beauty of chemistry in biological systems that can lead to profound advancements in biochemistry and pharmacology.

In summary, N-[2-hydroxy-1-(hydroxymethyl)heptadec-3-enyl]hexadecanamide is not merely a chemical formula; it is a gateway into understanding vital biochemical processes that sustain life and hold promise for innovative therapies.

Synonyms
C16-ceramide
24696-26-2
N-PALMITOYL-D-SPHINGOSINE
Ceramide (Egg, Chicken)
C16 Ceramide;Ceramide 16;D-erythro-C16-Ceramide;D-erythro-N-Hexadecanoylsphingenine;D-erythro-N-Palmitoylsphingosine;D-erythro-Delta4-Ceramide
SCHEMBL358660
DTXSID70865168
Hexadecanamide,N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-
4201-58-5
477243-06-4
DB-046523