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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
537-46-2
IUPAC name
N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide
State
State

At room temperature, methamphetamine is typically in a liquid state. However, it can also be encountered in a crystalline form, particularly in illegal drug formulations.

Melting point (Celsius)
3.60
Melting point (Kelvin)
276.75
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9470g/cm3
Appearence

Methamphetamine is a colorless volatile liquid at room temperature. It has a characteristic fishy odor.

Comment on solubility

Solubility of N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide

N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide demonstrates a complex solubility profile influenced by its chemical structure. Here are some key points regarding its solubility:

  • Polar Nature: The presence of hydroxyl (-OH) groups typically enhances solubility in polar solvents, such as water.
  • Aromatic Components: The phenyl groups may lead to increased solubility in organic solvents due to their hydrophobic nature.
  • Amide Functionality: Amides generally exhibit moderate solubility in a variety of solvents, yet this compound’s specific solubility will be dictated by both the steric and electronic effects of its substituents.
  • Temperature Influence: Solubility may increase with temperature, emphasizing the importance of environmental conditions.

To summarize, while the compound is expected to be soluble in polar solvents due to its hydroxyl groups, it may also have some degree of solubility in non-polar organic solvents due to aromatic interactions. The specific solubility can be quantitatively assessed through experiments that explore various solvent environments.

Interesting facts

Interesting Facts about N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide

N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide, often known in the scientific community for its unique structure, presents a fascinating opportunity for research and application. This compound, a derivative of nitrous amide, is noteworthy for various reasons:

  • Bioactivity: Research has suggested that compounds similar to nitrous amides can exhibit interesting biological properties, making them potential candidates in medicinal chemistry.
  • Synthetic versatility: The construction of this compound involves intricate synthetic methodologies that could pave the way for further modifications and derivative exploration.
  • Functional groups: The presence of multiple functional groups in its structure, such as hydroxyl and amide groups, offers diverse chemical reactivity. This allows for reactions such as acylation, alkylation, or even electrophilic substitutions.
  • Applications in research: Its unique combination of characteristics may contribute to studies in pharmacology, materials science, or asymmetric synthesis, showcasing the compound's potential utility in various fields.
  • Structure-activity relationship (SAR): The intricate design of this compound enables scientists to explore SAR in related compounds, potentially leading to more effective therapeutic agents.

As quoted in a recent article on chemical innovation, "The complexity and beauty of molecular design invite a deeper understanding of our world." This statement rings especially true when considering the potential implications of N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide in both theoretical and applied chemistry.

In conclusion, the exploration of such compounds expands our knowledge and illustrates the continuous journey of discovery in the field of chemistry.

Synonyms
N-Nitrosoephedrine
17608-59-2
N-nitrosopseudoephedrine
DTXSID1021035
DTXCID001035
alpha-(1-(Methylnitrosoamino)ethyl)benzenemethanol
1850-88-0
2-[methyl(nitroso)amino]-1-phenylpropan-1-ol
N-(1-hydroxy-1-phenylpropan-2-yl)-N-methylnitrous amide
N-(1-hydroxy-1-phenyl-propan-2-yl)-N-methyl-nitrous amide
2-[Methyl(nitroso)amino]-1-phenyl-1-propanol
2-(N-Methyl-N-nitrosoamino)-1-phenyl-1-propanol
1-Propanol, 2-(N-methyl-N-nitrosoamino)-1-phenyl-
alpha-(1-(N-Methyl-N-nitrosoamino)ethyl)benzyl alcohol
CHEMBL424344
alpha-(1-(Methylnitrosamino)ethyl)benzyl alcohol stereoisomer
Benzyl alcohol, alpha-(1-(methylnitrosamino)ethyl)-, stereoisomer
BENZYL ALCOHOL, alpha-(1-(N-METHYL-N-NITROSOAMINO)ETHYL)-
MFCD01081515
AKOS006275568
SY470788
EN300-25702089
N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-nitrous amide