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N-Hexadecanoyl morpholine

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Identification
Molecular formula
C27H49NO3
CAS number
61537-77-5
IUPAC name
N-[2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide
State
State

At room temperature, N-Hexadecanoyl morpholine is in a solid state. It has a stable crystalline form suitable for various chemical applications.

Melting point (Celsius)
82.00
Melting point (Kelvin)
355.15
Boiling point (Celsius)
502.00
Boiling point (Kelvin)
775.15
General information
Molecular weight
462.71g/mol
Molar mass
462.7110g/mol
Density
1.0458g/cm3
Appearence

N-Hexadecanoyl morpholine appears as an off-white to pale yellow solid. It has a waxy texture and crystalline structure.

Comment on solubility

Solubility of N-[2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide (C27H49NO3)

This compound exhibits unique solubility characteristics due to its molecular structure. The solubility can be influenced by several factors, including:

  • Hydrophobic and hydrophilic balance: The presence of both hydrophobic hexadecanamide chains and hydrophilic functional groups contributes to its complex solubility profile.
  • Solvent type: N-[2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide is expected to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) compared to aqueous solutions.
  • Temperature effects: Like many organic compounds, solubility may increase with temperature, making it beneficial to consider thermal conditions when dissolving this compound.
  • pH influence: The ionization of the compound can change with pH, which might lead to varying degrees of solubility in aqueous solutions.

In summary, the solubility of C27H49NO3 can be described as complex, typically favoring organic solvents over water, and is highly influenced by external conditions such as temperature and pH. Understanding the solubility of this compound is crucial for its practical applications in various fields.

Interesting facts

Exploring N-[2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide

N-[2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide, often referred to for its intriguing structural complexity, serves as a fascinating subject in both medicinal chemistry and pharmaceutical applications. Here are some interesting facts about this compound:

  • Pharmaceutical Potential: This compound has shown promise in various research studies focused on neuropharmacology and drug development, indicating its potential utility as a therapeutic agent.
  • Morpholine Linkage: The presence of a morpholinomethyl group in its structure can enhance lipophilicity and bioavailability, crucial properties for the development of effective therapeutic drugs.
  • Hydroxyl Group: The hydroxyl group can play a significant role in hydrogen bonding, influencing solubility and interaction with biological targets.
  • Aliphatic Chain: The hexadecanamide portion of the molecule - a long-chain amide - contributes to its hydrophobic characteristics, enhancing its membrane permeability, a key factor for many drugs.
  • Structure-Activity Relationship: Understanding the relationship between its structural components and biological activity is vital for optimizing the therapeutic efficacy of this compound.

As highlighted by research enthusiasts, “the intricacies in the design of such compounds often lead to groundbreaking discoveries in drug therapies.” With ongoing studies, the future of N-[2-hydroxy-1-(morpholinomethyl)-2-phenyl-ethyl]hexadecanamide could unlock new pathways for treatment modalities.

In summary, this compound exemplifies the complexity and potential of modern medicinal chemistry, merging interesting chemical functionalities with practical applications in health science. Its further exploration could yield revolutionary advancements in pharmacotherapy.

Synonyms
CHEBI:75125
N-[1-hydroxy-3-(morpholin-4-yl)-1-phenylpropan-2-yl]hexadecanamide
194038-29-4
SCHEMBL840939
CHEMBL1241757
DTXSID90274394
N-(1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl)hexadecanamide
1-phenyl-2-palmitoylamino-3-morpholino-1-propanol
1-phenyl-2-hexadecanoylamino-3-morpholino-1-propanol
Q27145139
N-[1-hydroxy-3-(morpholin-4-yl)-1-phenylpropan-2-yl]palmitamide