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Formoterol

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Identification
Molecular formula
C19H24N2O4
CAS number
73573-87-2
IUPAC name
N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]ethyl]phenyl]formamide
State
State

The compound is considered stable at room temperature and is typically processed into modalities that suit its use, such as inhalants or tablets.

Melting point (Celsius)
152.15
Melting point (Kelvin)
425.30
Boiling point (Celsius)
395.10
Boiling point (Kelvin)
668.25
General information
Molecular weight
344.41g/mol
Molar mass
344.4060g/mol
Density
0.7020g/cm3
Appearence

Formoterol appears as a white or off-white crystalline powder. It is typically provided in its inhalation forms mixed with other substances, as the pure form might be used alone sparingly.

Comment on solubility

Solubility of N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]ethyl]phenyl]formamide

The solubility of N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]ethyl]phenyl]formamide (C19H24N2O4) can be influenced by various factors. Here are some key considerations:

  • Polarity: The presence of hydroxyl groups (–OH) suggests that this compound may have polar characteristics, which can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the -OH groups to form hydrogen bonds may lead to greater solubility in aqueous solutions, making it more soluble than many compounds without such functional groups.
  • Alkyl and Aromatic Groups: The 4-methoxyphenyl and ethyl moieties may contribute to hydrophobic interactions, potentially reducing solubility in highly polar environments while increasing solubility in organic solvents.

In general, one might find that:

  1. If dissolved in water, it may exhibit decent solubility due to polar interactions.
  2. In non-polar solvents, the solubility may be limited due to hydrophobic character.
  3. Experimental data is necessary to confirm actual solubility parameters.

In summary, while theoretical implications suggest a certain level of solubility in polar solvents, empirical testing is crucial to ascertain the precise solubility profile of this compound.

Interesting facts

Interesting Facts about N-[2-Hydroxy-5-[1-Hydroxy-2-[[2-(4-Methoxyphenyl)-1-Methyl-Ethyl]Amino]Ethyl]Phenyl]Formamide

This intriguing compound, known as N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methyl-ethyl]amino]ethyl]phenyl]formamide, has several notable characteristics and applications that make it a fascinating subject of study in the field of chemistry.

Key Features:

  • Pharmaceutical Relevance: This compound features functional groups that are often associated with biologically active molecules, highlighting its potential significance in drug design and medicinal chemistry.
  • Structural Complexity: The intricate structure, with multiple phenyl rings and heteroatoms, contributes to various chemical properties, affecting interactions in biochemical environments.
  • Synthetic Pathways: Understanding the synthesis of this compound can provide insights into organic synthesis techniques, particularly in creating compounds with specific amine functionalities.
  • Research Potential: Scientists are constantly exploring compounds like this for their potential pharmacological activity, including anti-inflammatory or anticancer properties.

As a chemistry student or scientist, appreciating the intricacies and possibilities of such compounds opens doors to a broader understanding of chemical interactions.

Did You Know?

  • This compound may serve as a model to study receptor binding in drug discovery.
  • The dual amine and alcohol functionality enables various chemical reactions, including acetylation and conjugation with other biomolecules.

Such compounds represent the elegance of chemistry, where the slightest variation in structure can lead to significant changes in activity and interaction. Engaging with them is not just an academic exercise; it can lead to groundbreaking research that impacts medicine and pharmacology.

Synonyms
formoterol
73573-87-2
128954-45-0
Formoterolum [INN-Latin]
Oxeze/Oxis
n-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide
Formoterolum
N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
Foradil
Innovair
Fluir
FORMOTEROL FUMARATE
CHEBI:63082
Racemic formoterol
Formoterol (INN)
(+-)-Formoterol
Formoterolum (INN-Latin)
UNII-5ZZ84GCW8B
HSDB 7287
2'-hydroxy-5'-(1-hydroxy-2-((p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide
2'-hydroxy-5'-{1-hydroxy-2-[(p-methoxy-alpha-methylphenethyl)amino]ethyl}formanilide
N-[2-hydroxy-5-(1-hydroxy-2-{[2-(4-methoxyphenyl)-1-methylethyl]amino}ethyl)phenyl]formamide
Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, [R-(R*,S*)]-
Oxis (TN)
DTXSID1023077
BD-40A
(+-)-2'-Hydroxy-5'-((RS)-1-hydroxy-2-(((RS)-p-methoxy-alpha-methylphenethyl)amino)ethyl)formanilide
Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-; N-[2-Hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide
n-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide
rel-N-
CGP-25827A
NCGC00181126-01
SCHEMBL349579
CHEBI:5147
GTPL3465
3-formylamino-4-hydroxy-alpha-
CHEMBL1256786
DTXCID4065311
SCHEMBL15856256
BDBM86453
DTXSID20860603
R03AC13
(+/-)-2'-hydroxy-5'-
BPZSYCZIITTYBL-UHFFFAOYSA-N
FORMAMIDE, N-(2-HYDROXY-5-(1-HYDROXY-2-((2-(4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHYL)PHENYL)-
HWA41436
AC-459
STL450992
AKOS015961179
AT22502
DB00983
SB17482
NSC_3083544
AS-14186
CAS_73573-87-2
NS00008796
C07805
D07990
EN300-7480042
L000259
Q637247
126587-85-7
N-(2-hydroxy-5-((1RS)-1-hydroxy-2-(((2RS)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide
N-[2-hydroxy-5-[(1rs)-1-hydroxy-2-[[(1rs)-2(4methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl] formamide