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Phenylacetyl hydroxamic acid

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Identification
Molecular formula
C10H11NO3
CAS number
1576-35-8
IUPAC name
N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide
State
State

At room temperature, phenylacetyl hydroxamic acid is in a solid state. It exists as a white crystalline powder.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
395.00
Boiling point (Kelvin)
668.15
General information
Molecular weight
180.17g/mol
Molar mass
180.1730g/mol
Density
1.3100g/cm3
Appearence

Phenylacetyl hydroxamic acid typically appears as a crystalline solid. It possesses a white to off-white coloration, indicative of its purity and the arrangement of its crystal lattice.

Comment on solubility

Solubility of N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide

The solubility of N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide, a compound characterized by its complex structure, can be influenced by several factors. Understanding its solubility profile is essential for practical applications. Here are key aspects to consider:

  • Polarity: The presence of both hydrophobic phenyl and hydrophilic hydroxyl and amino groups leads to a balance between polar and non-polar characteristics, impacting solubility in various solvents.
  • Solvent Types: Generally, compounds with similar polarity dissolve well. Thus:
    • High solubility may be observed in polar solvents such as water and alcohols due to hydrogen bonding.
    • Low solubility could occur in non-polar solvents like hydrocarbons.
  • Temperature Effects: As with many organic compounds, increasing the temperature can enhance solubility by facilitating interactions between solute and solvent.

In conclusion, the solubility of N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide is dictated by an intricate interplay between its molecular structure and external factors such as solvent type and temperature. This highlights the necessity for careful evaluation in experimental settings, ensuring optimal conditions for dissolution and usability.

Interesting facts

Interesting Facts about N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide

N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide, often referred to in scientific circles for its intriguing chemical properties and potential applications, possesses some fascinating characteristics worth noting:

  • Biological Significance: This compound has been studied for its potential roles in various biological processes, particularly in the realm of medicinal chemistry. Its structure allows it to interact with biological targets, raising the possibility of therapeutic uses.
  • Structural Diversity: The presence of a hydroxyamino group in its structure adds a unique aspect to its chemical reactivity and compatibility with other compounds. This structural diversity is often a subject of interest in drug design.
  • Chemical Stability: Researchers find that the compound exhibits a certain degree of stability under varying conditions, making it a suitable candidate for further studies in different environments.
  • Research Applications: Its use in research extends beyond medicinal applications. N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide has been employed in studies involving biochemistry and molecular biology, particularly in understanding enzyme interactions.
  • Future Directions: As investigations into its properties continue, scientists are hopeful for its potential applications in the design of novel therapeutics. The compound holds promise as a starting point for synthesizing new drugs.

Overall, N-[2-(hydroxyamino)-2-oxo-ethyl]-2-phenyl-acetamide serves as a striking example of how even a single compound can open up pathways to extensive research and innovation in chemistry and medicine.

Synonyms
2-(2-Phenylacetamido)acetohydroxamic acid
4543-32-2
ACETOHYDROXAMIC ACID, 2-(2-PHENYLACETAMIDO)-
Phenaceturohydroxamic acid
N-(Phenylacetyl)glycinohydroxamic acid
N-(2-(Hydroxyamino)-2-oxoethyl)benzeneacetamide
Benzeneacetamide, N-(2-(hydroxyamino)-2-oxoethyl)-
CHEMBL4084415
DTXSID20196510