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N-Acetylanthranilic acid

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Identification
Molecular formula
C9H9NO3
CAS number
89-52-1
IUPAC name
N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide
State
State

This compound exists as a solid at room temperature, typically appearing as crystalline powder.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
165.17g/mol
Molar mass
165.1650g/mol
Density
1.3582g/cm3
Appearence

N-Acetylanthranilic acid appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide

N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide exhibits notable solubility characteristics, primarily attributed to its molecular structure that includes both hydrophilic and hydrophobic components. Here are some key aspects regarding its solubility:

  • Solvent Compatibility: This compound is likely to be soluble in polar solvents such as water and alcohols due to the presence of the hydroxyamino group, which can engage in hydrogen bonding.
  • Temperature Dependence: As with many organic compounds, solubility may improve with increasing temperature, allowing more solute to dissolve in a given amount of solvent.
  • Influence of pH: The solubility can also vary with pH levels, especially because the amino group can gain or lose protons, affecting its interaction with water.
  • Crystalline vs. Amorphous Forms: The physical form of N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide may impact solubility; generally, amorphous compounds tend to be more soluble compared to their crystalline counterparts.

Overall, the solubility of N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide is a complex interplay of its chemical structure, solvent characteristics, and environmental conditions. As a rule of thumb, compounds containing both polar functional groups and aromatic rings can display variable solubility profiles depending on these factors.

Interesting facts

Interesting Facts about N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide

N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide is a compound that has garnered interest due to its unique structural and functional characteristics. Here are some noteworthy aspects to consider:

  • Biological Relevance: This compound is part of a class that has implications in medicinal chemistry, particularly in the study of enzyme inhibitors and potential therapeutic agents.
  • Functional Groups: The presence of both a hydroxyamino group and an amide functional group in its structure can lead to significant chemical reactivity, which is crucial for its applications in drug development.
  • Synthetic Versatility: The synthetic pathways leading to N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide reflect the compound's versatility, allowing for modifications that can enhance its target specificity in various biological systems.
  • Interaction Mechanisms: As with many compounds, understanding how N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide interacts with biological macromolecules can inform its potential utility. These interactions often depend on the conformation and charge distribution of the molecule.
  • Future Prospects: Ongoing research may uncover novel applications of this compound in fields such as pharmacology and biochemistry, particularly in deciphering its role in cellular pathways and disease mechanisms.

In summary, N-[2-(hydroxyamino)-2-oxo-ethyl]benzamide exemplifies how a single compound can serve multiple purposes in scientific inquiry. Its multidimensional utility underscores the importance of exploring such compounds in-depth.

Synonyms
Hippurohydroxamic acid
1499-54-3
N-[2-(hydroxyamino)-2-oxoethyl]benzamide
Benzamide, N-[2-(hydroxyamino)-2-oxoethyl]-
Benzoylaminoacetohydroxamic acid
(2-Benzamido)acetohydroxamic acid
N-(2-Hydroxyamino)-2-(oxoethyl)benzamide
hippurohydroxamic
ACETOHYDROXAMIC ACID, 2-BENZAMIDO-
Benzamide, N-(2-hydroxyamino)-2-(oxoethyl)-
SCHEMBL7412271
CHEMBL4088851
DTXSID10164425
N-((hydroxycarbamoyl)methyl)benzamide
AKOS006243113
DB-352170
AL-398/40365670
VGU