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N-(2-hydroxyethyl)acetamide

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Identification
Molecular formula
C4H9NO2
CAS number
110-26-9
IUPAC name
N-(2-hydroxyethyl)acetamide
State
State

At room temperature, N-(2-hydroxyethyl)acetamide is generally in a solid state.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.00
Boiling point (Celsius)
285.60
Boiling point (Kelvin)
558.80
General information
Molecular weight
103.12g/mol
Molar mass
103.1120g/mol
Density
1.0807g/cm3
Appearence

N-(2-hydroxyethyl)acetamide typically appears as a colorless or white crystalline solid. It is often odorless and can appear as a powder or crystals.

Comment on solubility

Solubility of N-(2-hydroxyethyl)acetamide

N-(2-hydroxyethyl)acetamide, often recognized for its role in various chemical processes, exhibits notable solubility characteristics that are pivotal to its applications.

Key Points on Solubility:

  • Solvent Compatibility: It is generally soluble in water due to the presence of the hydroxyl group, which promotes hydrogen bonding.
  • Polarity: The molecule's polar nature allows it to interact favorably with other polar solvents, enhancing its solubility profile.
  • Temperature Effects: Like many amides, an increase in temperature can lead to an increase in solubility, making it more versatile in industrial applications.
  • Limited Organic Solubility: While it is soluble in water, it may exhibit limited solubility in non-polar organic solvents, affecting its usage scenarios.

This solubility behavior is significant as it not only influences the compound's practical uses but also its reactivity and interactions in various chemical environments. Thus, understanding the solubility of N-(2-hydroxyethyl)acetamide is key for optimizing its applications in both laboratory and industrial settings.

Interesting facts

Interesting Facts about N-(2-hydroxyethyl)acetamide

N-(2-hydroxyethyl)acetamide, often referred to as HEAA, is a fascinating compound that has been gaining attention in various fields due to its versatile properties. Here are some intriguing aspects of this compound:

  • Biochemical Applications: HEAA is primarily recognized for its role in the pharmaceutical and biochemical industries. It serves as a valuable intermediate in the synthesis of numerous bioactive molecules.
  • Hydrophilicity: The presence of a hydroxyethyl group contributes to its hydrophilic nature, making it an excellent candidate for applications in drug formulation where water solubility is desirable.
  • Potential in Biotechnology: This compound is being explored for its potential use in biotechnological applications, particularly in the formulation of biocompatible materials and as a component in hydrogels.
  • Safety Profile: Studies indicate that HEAA exhibits low toxicity levels, which is a significant factor for its consideration in various applications, ensuring safety for both users and the environment.
  • Versatile Functionality: The functional groups present in HEAA allow for diverse reactivity, making it a useful building block in organic synthesis, especially in the preparation of amides and other derivatives.

In conclusion, N-(2-hydroxyethyl)acetamide showcases a remarkable combination of properties that enable it to play diverse roles across multiple disciplines. As research continues, who knows what new applications and discoveries might emerge from this intriguing compound?

As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." In the world of chemical compounds like HEAA, every new insight could lead to exciting breakthroughs!

Synonyms
N-(2-Hydroxyethyl)acetamide
N-Acetylethanolamine
142-26-7
2-Acetamidoethanol
Acetamide, N-(2-hydroxyethyl)-
Acetamide MEA
Acetylcolamine
2-Acetylaminoethanol
N-Ethanolacetamide
N-Acetyl-2-aminoethanol
Hydroxyethyl acetamide
N-Acetyl ethanolamine
ACETYLETHANOLAMINE
N-2-Hydroxyethylacetamide
Acetic monoethanolamide
beta-Hydroxyethylacetamide
N-beta-Hydroxyethylacetamide
NSC 5999
HSDB 2713
.beta.-Hydroxyethylacetamide
EINECS 205-530-8
BRN 1811708
A9O0818TWD
Acetic acid amide, N-(2-hydroxyethyl)-
DTXSID6044804
CHEBI:74687
AI3-02836
NSC-5999
MFCD00002836
ACETAMIDE MEA [VANDF]
acetamide, N-(2-hydroxyethyl)
DTXCID4024804
ACETYLETHANOLAMINE [HSDB]
N-(.beta.-Hydroxyethyl)acetamide
4-04-00-01535 (Beilstein Handbook Reference)
N-Acetylethanolamine (~90%)
UNII-A9O0818TWD
NEthanolacetamide
2Acetamidoethanol
Hetamide MA
Carsamide AMEA
Lipamide MEAA
Amidex AME
NAcetylethanolamine
Upamide ACMEA
2Acetylaminoethanol
NAcetyl ethanolamine
NAcetyl2aminoethanol
N-acetyl-ethanolamine
Schercomid AME 70
Foamid AME-70
Foamid AME-75
Mackamide AME-100
Foamid AME-100
betaHydroxyethylacetamide
Incromectant AMEA-70
NbetaHydroxyethylacetamide
Incromectant AMEA-100
N(2Hydroxyethyl)acetamide
n-2-hydroxyethyl-acetamide
WLN: Q2MV1
SCHEMBL48502
ACETAMIDE MEA [INCI]
N-(2-hydroxyethyl)-acetamide
N-(beta-Hydroxyethyl)acetamide
N-(2-hydroxy-ethyl)-acetamide
SCHEMBL9597207
CHEMBL3188272
NSC5999
Tox21_301724
Acetic acid amide, N(2hydroxyethyl)
N-Acetylethanolamine, technical grade
STL283925
AKOS005206796
CS-W013689
FD10637
FS-4296
NCGC00256051-01
CAS-142-26-7
FA183124
SY007881
DB-000300
A0075
A1935
NS00001024
EN300-15590
ACETIC ACID, AMIDE, N(2-HYDROXYETHYL)-
Q27144824