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Myristamide MEA

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Identification
Molecular formula
C16H33NO2
CAS number
142-78-9
IUPAC name
N-(2-hydroxyethyl)tetradecanamide
State
State

At room temperature, Myristamide MEA is a solid. It may appear in a waxy consistency, commonly used in cosmetic and personal care formulations.

Melting point (Celsius)
72.00
Melting point (Kelvin)
345.15
Boiling point (Celsius)
405.70
Boiling point (Kelvin)
678.85
General information
Molecular weight
283.47g/mol
Molar mass
283.4710g/mol
Density
0.9800g/cm3
Appearence

Myristamide MEA appears as a white to off-white solid. It can appear waxy or as flakes, depending on its formulation and purity.

Comment on solubility

Solubility of N-(2-hydroxyethyl)tetradecanamide

N-(2-hydroxyethyl)tetradecanamide, a compound with a long hydrophobic alkyl chain, exhibits intriguing solubility characteristics based on its unique structure. Its solubility can be influenced by several factors:

  • Polar Head Group: The presence of the -OH (hydroxy) functional group increases its polarity, which facilitates solubility in polar solvents, such as water.
  • Hydrophobic Tail: The long tetradecanamide (C14H29NO) chain is hydrophobic, making it less soluble in water compared to smaller molecules.
  • Solvent Type: In non-polar solvents (like hexane or heptane), the compound is more likely to dissolve due to the compatibility of its hydrophobic chain with the non-polar environment.

Interestingly, the balance between hydrophilic and hydrophobic characteristics creates a unique scenario where N-(2-hydroxyethyl)tetradecanamide can exhibit variable solubility depending on the environment:

  • **Soluble in:** Water, ethanol, and other polar solvents.
  • **Slightly soluble in:** Organic solvents.
  • **Insoluble in:** Hydrocarbons due to the overwhelming hydrophobic nature of the long alkyl chain.

This dual nature of solubility makes N-(2-hydroxyethyl)tetradecanamide a fascinating compound for applications in diverse fields, particularly in formulations where both hydrophilic and hydrophobic properties are beneficial.

Interesting facts

Interesting Facts about N-(2-hydroxyethyl)tetradecanamide

N-(2-hydroxyethyl)tetradecanamide, commonly known as a surfactant and fatty amide, is a fascinating compound that emerges from the fusion of biology and chemistry. Here are some key points that showcase its significance:

  • Biocompatibility: This compound is particularly noted for its compatibility with biological systems, making it an important candidate in biomedical applications.
  • Surfactant Properties: Due to its amphiphilic nature, it possesses excellent surfactant properties, which allow it to reduce surface tension and improve the wetting properties of various formulations.
  • Pharmaceutical Use: It has found a role in drug delivery systems, enhancing the solubility and bioavailability of hydrophobic drugs.
  • Cosmetic Applications: Its hydrophilic-lipophilic balance (HLB) makes it suitable for use in cosmetic products where moisturizing effects and skin compatibility are desired.
  • Synthetic Versatility: N-(2-hydroxyethyl)tetradecanamide is synthesized through various methods, allowing for the exploration of different substitution patterns in the amide moiety, which can lead to diverse chemical properties.

As a compound, N-(2-hydroxyethyl)tetradecanamide stands at the crossroads of chemistry and practical application, illustrating how even simple amides can have profound implications in real-world scenarios. Its dual functionality in both enhancing product performance and biocompatibility underscores the broad potential of chemical compounds in innovation and development.

In summary, N-(2-hydroxyethyl)tetradecanamide is a prime example of how chemistry can contribute to advancements in health and beauty through its versatile applications. As research continues, the scope of this compound may expand, revealing even more opportunities within the fields of materials science and pharmaceuticals.

Synonyms
142-58-5
N-(2-HYDROXYETHYL)TETRADECANAMIDE
N-(2-Hydroxyethyl)myristamide
Myristamide MEA
Myristic monoethanolamide
myristoyl ethanolamide
N-myristoylethanolamine
Tetradecanamide, N-(2-hydroxyethyl)-
Comperlan MM
Myristoyl-EA
Schercomid MME
Loramine MY 228
Myristoyl-ethanolamine
Myristyl monoethanolamide
Myristoyl monoethanolamide
6CYG57WXZ0
N-(Tetradecanoyl)-ethanolamine
HSDB 5640
tetradecanoyl ethanolamide
EINECS 205-546-5
Monoethanolamine myristic acid condensate
CHEMBL5277451
DTXSID0042452
NAE 14:0
N-(2-HYDROXYETHYL)TETRADECANAMIDE [HSDB]
UNII-6CYG57WXZ0
N-(tetradecanoyl)ethanolamine
MFCD02670245
N-(myristoyl)ethanolamine
N-tetradecanoylethanolamine
SCHEMBL308261
MYRISTAMIDE MEA [INCI]
GTPL5221
DTXCID8022452
CHEBI:85262
NAE14:0
JHIXEZNTXMFXEK-UHFFFAOYSA-N
Tetradecanamide, N(2hydroxyethyl)
N-(2-hydroxyethyl)-tetradecanamide
BDBM50408838
LMFA08040042
AKOS002676442
AM 3165
BS-15372
HY-119723
CS-0077862
NS00013870
A10816
TETRADECANOIC ACID (2-HYDROXY-ETHYL)-AMIDE
Q27083876