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N'-(2-hydroxyphenyl)pyridine-4-carboxamidine

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Identification
Molecular formula
C12H11N3O
CAS number
135051-50-8
IUPAC name
N'-(2-hydroxyphenyl)pyridine-4-carboxamidine
State
State

At room temperature, this compound is typically in a solid state. It is primarily found as powder due to its crystalline nature.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.20
Boiling point (Celsius)
487.10
Boiling point (Kelvin)
760.20
General information
Molecular weight
213.24g/mol
Molar mass
213.2400g/mol
Density
1.3261g/cm3
Appearence

This compound is usually a crystalline solid. It can appear as a white to off-white powder depending on its purity and specific synthesis method.

Comment on solubility

Solubility of N'-(2-hydroxyphenyl)pyridine-4-carboxamidine

N'-(2-hydroxyphenyl)pyridine-4-carboxamidine is a fascinating compound with notable characteristics regarding its solubility. It typically displays solubility in polar organic solvents, which can be attributed to its functional groups that enhance interactions with solvent molecules. Here are some key points to consider:

  • Solvents: This compound is usually soluble in ethanol and DMSO, while its solubility in water may be limited due to its hydrophobic regions.
  • pH Sensitivity: The presence of amidine groups can influence solubility based on the pH of the solution, potentially increasing its solubility at different pH levels.
  • Temperature Influence: Increased temperature can enhance solubility for many compounds, and this one may follow the same trend, but specific studies would be necessary to confirm.
  • Complexation: In certain conditions, N'-(2-hydroxyphenyl)pyridine-4-carboxamidine can form complexes with metals or other ions, which might also affect its overall solubility.

Overall, the solubility of N'-(2-hydroxyphenyl)pyridine-4-carboxamidine fascinates researchers and illustrates the diverse behavior of organic compounds in various environments. Understanding these solubility characteristics is crucial for its applications in pharmacology and materials science.

Interesting facts

Exploring N'-(2-hydroxyphenyl)pyridine-4-carboxamidine

N'-(2-hydroxyphenyl)pyridine-4-carboxamidine, often regarded for its intriguing structural features, showcases the fascinating interplay between organic chemistry and pharmacology. This compound is a derivative of an aromatic amine, an important class of compounds known for their versatile applications in the synthesis of various pharmaceuticals.

Notable Characteristics

  • Biological Activity: Several studies suggest that its structural components may contribute to significant biological activities, including potential anti-inflammatory and anticancer properties.
  • Binding Affinity: The presence of the carboxamidine functional group may facilitate binding with specific biological targets, enhancing its potential use in drug development.
  • Structural Complexity: The combination of the pyridine and phenolic moieties makes N'-(2-hydroxyphenyl)pyridine-4-carboxamidine a subject of interest for researchers exploring complex molecular interactions.

As a student of chemistry, delving into compounds like this one opens up a world of possibilities in thinking about how molecular structure correlates with function. The exploration of ligand-receptor interactions is a vital part of medicinal chemistry, and this compound sits at the crossroads of these explorations.

In essence, N'-(2-hydroxyphenyl)pyridine-4-carboxamidine is more than just a compound; it’s a gateway into understanding how nuanced changes at the molecular level can profoundly impact biological efficacy. As scientists unravel its mysteries, we could potentially see it play pivotal roles in innovative therapeutic strategies.

Synonyms
23564-33-2
ISONICOTINAMIDINE, N-(o-HYDROXYPHENYL)-
RefChem:1087595
N-(o-Hydroxyphenyl)isonicotinamidine
BRN 0476734
4-Pyridinecarboximidamide, N-(2-hydroxyphenyl)-