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Methoxyphenyl acetophenone

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Identification
Molecular formula
C16H15NO3
CAS number
92986-57-3
IUPAC name
N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide
State
State

The compound is in a solid state at room temperature.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
243.30g/mol
Molar mass
243.2740g/mol
Density
1.1710g/cm3
Appearence

This compound appears as a solid with a pale yellow color. It often comes in crystalline form or as a powder.

Comment on solubility

Solubility of N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide

The solubility of N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide can be influenced by several factors, including the chemical structure and the presence of functional groups within the compound. This compound features both hydrophilic and hydrophobic regions, which contribute to its solubility characteristics.

Factors Affecting Solubility

  • Polarity: The presence of the methoxy group (-OCH3) increases polarity, which can enhance solubility in polar solvents like water to a certain extent.
  • Hydrogen Bonding: The amide functional group in the structure can engage in hydrogen bonding, further affecting solubility by potentially allowing interaction with water molecules.
  • Molecular Size: The overall size and structure may limit solubility in some non-polar solvents, as larger molecules typically experience reduced interaction with solvent particles.

In practical terms, when considering solubility for applications, it is important to note that:

  1. Often, the compound may show limited solubility in cold water but may dissolve better in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  2. Experimental solubility data would be necessary for specific concentrations at varying temperatures.

In conclusion, understanding the solubility of N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide is crucial for its application in various chemical reactions and processes. Testing in diverse solvents will provide valuable insight into its practical solubility behavior.

Interesting facts

Interesting Facts about N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide

N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide is a compound that showcases an intriguing intersection of medicinal chemistry and organic synthesis. Here are some fascinating insights about this compound:

  • Potential Pharmaceutical Applications: This compound belongs to a class of amides which are notable for their biological activity. The structure hints at the potential for this compound to play a role in pharmaceuticals, possibly demonstrating anti-inflammatory or analgesic properties.
  • Synthetic Pathways: The synthesis of N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide can involve various methodologies, including acylation reactions and condensation approaches. This provides ample opportunity for a chemistry student to explore advanced organic synthesis techniques.
  • Substituent Effects: The presence of the methoxy group and phenyl group in this compound can significantly influence its chemical behavior, including reactivity and binding affinity in biological systems. Understanding these effects can deepen your knowledge of structure-activity relationships (SAR) in drug design.
  • Research Interest: Compounds with similar structures have drawn attention in scientific research for their potential as enzyme inhibitors or in derivative development for targeted therapies, especially in cancer treatment. Exploring this aspect can provide insights into current trends in medicinal chemistry.
  • Interdisciplinary Connections: This compound highlights the connection between various fields such as organic chemistry, pharmacology, and biochemistry, demonstrating how interdisciplinary approaches can lead to groundbreaking discoveries in drug development.

In summary, N-(2-methoxyphenyl)-3-oxo-3-phenyl-propanamide is not only an intriguing compound but also a stepping stone into the broader realm of organic chemistry, with possible applications and implications that extend into the field of medicine. As you delve into its synthesis and potential effects, you will find a wealth of knowledge waiting to be explored!

Synonyms
N-(2-methoxyphenyl)-3-oxo-3-phenylpropanamide
92-16-0
2-Benzoyl-2'-methoxyacetanilide
Benzoylacet-o-anisidide
BRN 2742898
EINECS 202-132-6
Benzenepropanamide, N-(2-methoxyphenyl)-beta-oxo-
Benzenepropanamide, N-(2-methoxyphenyl)-.beta.-oxo-
o-ACETANISIDIDE, BENZOYL-
N-(2-Methoxyphenyl)-beta-oxobenzenepropanamide
DTXSID9059042
2-Benzoyl-o-acetanisidide
alpha-BENZOYL-o-METHOXY ACETANILIDE
Oprea1_238148
MLS001198317
5K83PZU2L5
SCHEMBL3315763
CHEMBL1330315
DTXCID7048748
alpha-benzoyl-o-methoxyacetanilide
HMS2856G18
STK711610
AKOS001754896
NCGC00245894-01
SMR000559163
CS-0330306
NS00039435
AF-628/30935027
SR-01000525560
SR-01000525560-1