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N-(2-methoxyphenyl)aziridine-1-carboxamide

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Identification
Molecular formula
C10H12N2O2
CAS number
98107-60-3
IUPAC name
N-(2-methoxyphenyl)aziridine-1-carboxamide
State
State

At room temperature, N-(2-methoxyphenyl)aziridine-1-carboxamide exists in a solid state. It is often handled and stored under controlled conditions to maintain its stability and purity.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.00
Boiling point (Celsius)
289.00
Boiling point (Kelvin)
562.00
General information
Molecular weight
178.21g/mol
Molar mass
178.2050g/mol
Density
1.2265g/cm3
Appearence

N-(2-methoxyphenyl)aziridine-1-carboxamide is typically a crystalline solid. It may appear as off-white or pale yellow crystals or powder. The compound is often stored in a dry, light-protected environment to prevent degradation.

Comment on solubility

Solubility of N-(2-methoxyphenyl)aziridine-1-carboxamide

N-(2-methoxyphenyl)aziridine-1-carboxamide is a compound that exhibits unique solubility characteristics, influenced by its chemical structure. The solubility of this compound can be analyzed based on several factors:

  • Polarity: The presence of the 2-methoxyphenyl group introduces polar characteristics to the molecule, which could enhance its solubility in polar solvents.
  • Hydrogen Bonding: The carboxamide functional group can engage in hydrogen bonding, potentially improving solubility in hydrogen-bond-donating solvents such as water.
  • Solvent Compatibility: This compound may dissolve well in organic solvents like ethanol and dimethyl sulfoxide (DMSO), while its solubility in hydrocarbons could be limited due to its polar nature.
  • Temperature Dependence: Solubility can vary with temperature, where increased temperatures typically enhance the solubility of organic compounds.

In summary, while specific quantitative solubility data might not be readily available, the overall solubility of N-(2-methoxyphenyl)aziridine-1-carboxamide can be expected to be moderate in polar solvents and variable depending on the medium. A thorough understanding of solubility is essential for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts about N-(2-methoxyphenyl)aziridine-1-carboxamide

N-(2-methoxyphenyl)aziridine-1-carboxamide is a fascinating compound that showcases the diversity of organic chemistry and its potential applications. Here are some intriguing aspects of this compound:

  • Structural Uniqueness: The aziridine ring, a three-membered cyclic amine, is known for its strain and reactivity, making it an excellent candidate for various chemical reactions and transformations.
  • Functional Groups: The incorporation of the carboxamide functional group provides this compound with unique properties that can influence its solubility and reactivity under different conditions.
  • Medicinal Chemistry: Compounds containing aziridine rings have shown promise in medicinal chemistry, often serving as intermediates in the synthesis of bioactive molecules. N-(2-methoxyphenyl)aziridine-1-carboxamide could potentially play a role in the development of new pharmaceuticals.
  • Versatile Synthesis: The presence of the methoxy group enhances the compound's potential for various synthetic pathways, allowing chemists to manipulate its structure for specific applications. This versatility is crucial in drug design and chemical research.
  • Research Applications: Current research often explores the use of aziridines in the fields of polymer science, organocatalysis, and asymmetric synthesis, highlighting the compound's significance in advancing chemical knowledge.

In summary, N-(2-methoxyphenyl)aziridine-1-carboxamide not only exemplifies a complex and intriguing molecular structure but also represents the endless possibilities in organic synthesis and application in medicinal chemistry. As the field of chemistry continues to evolve, compounds like this will undoubtedly pave the way for innovative discoveries and developments.

Synonyms
3647-16-3
BRN 1345654
1-AZIRIDINECARBOXAMIDE, N-(o-METHOXYPHENYL)-
1-(1-Aziridinyl)-N-(o-methoxyphenyl)formamide
Formamide, 1-(1-aziridinyl)-N-(o-methoxyphenyl)-
DTXSID10189976
DTXCID70112467