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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]-2-phenyl-acetamide
State
State

Fentanyl is a solid at room temperature. It is often synthesized for medical use in various forms, including patches, lozenges, and injectables.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.65
Boiling point (Celsius)
474.82
Boiling point (Kelvin)
747.97
General information
Molecular weight
336.47g/mol
Molar mass
336.4710g/mol
Density
1.2261g/cm3
Appearence

Fentanyl typically appears as a white to off-white powder. It can also be found as a colorless solution when dissolved for intravenous use.

Comment on solubility

Solubility Insights

N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]-2-phenyl-acetamide, often referred to as a complex organic compound, displays unique solubility characteristics that are noteworthy.

Generally, the solubility of such compounds can be influenced by various factors:

  • Polarity: The presence of multiple aromatic rings and a piperidyl group suggests a degree of hydrophobicity, potentially limiting its solubility in polar solvents like water.
  • Solvent Choice: This compound may exhibit better solubility in organic solvents, such as dichloromethane or ethanol, which can accommodate its hydrophobic nature.
  • Temperature: Increasing the temperature often enhances solubility; thus, higher temperatures might facilitate better dissolution in suitable solvents.
  • pH Sensitivity: Depending on the pH of the environment, ionic groups may alter, impacting solubility significantly. For example, acidic conditions might protonate certain groups, increasing aqueous solubility.

Overall, while N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]-2-phenyl-acetamide may not readily dissolve in **water**, it holds potential for solubility in non-polar and mildly polar organic solvents, making it a fascinating subject for further research.

Interesting facts

Interesting Facts about N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]-2-phenyl-acetamide

This intriguing compound, known for its complex structure, is often studied for its potential medicinal applications. Here are some fascinating insights:

  • Pharmacological Interest: Compounds with similar structures have been investigated for their effects on the central nervous system, potentially aiding in treatments for various neurological and psychiatric disorders.
  • Structural Complexity: The dual presence of the acetamide group and a piperidine ring in the molecule contributes to its interesting properties. This complexity opens doors for diverse interactions within biological systems.
  • Synthetic Pathways: The synthesis of this compound likely involves sophisticated organic reactions, including aldol condensations and amine functionalization, highlighting the creativity required in organic chemistry.
  • Research Applications: Due to its structural characteristics, it may serve as a scaffold for the development of new drugs, showcasing the importance of structure-activity relationships in pharmaceutical chemistry.
  • Theoretical Studies: Computational chemistry approaches, like molecular docking and quantitative structure-activity relationship (QSAR) modeling, may be employed to predict the behavior and efficiency of this compound.

As stated by a noted chemist, "The beauty of synthetic chemistry lies not only in the products but in the journey of their creation." This sentiment rings true when exploring compounds like N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]-2-phenyl-acetamide, where every molecular aspect opens up new avenues for scientific inquiry.