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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide
State
State

At room temperature, fentanyl is typically a solid. It is often formulated in various forms for pharmaceutical applications, such as patches and lozenges.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.70
Boiling point (Celsius)
379.50
Boiling point (Kelvin)
652.70
General information
Molecular weight
336.47g/mol
Molar mass
336.4700g/mol
Density
1.2267g/cm3
Appearence

Fentanyl is a white to off-white solid with a crystalline appearance. It may also appear as a powder, often colorless or off-white.

Comment on solubility

Solubility of N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide

N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide is a fascinating compound when it comes to its solubility characteristics.

Solubility Characteristics:

This compound exhibits variable solubility depending on the solvent used. Here are some key points to consider:

  • Organic Solvents: Generally, N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide is more soluble in organic solvents. Compounds with large aromatic or hydrophobic groups, like this one, tend to dissolve better in non-polar or moderately polar solvents.
  • Water Solubility: Its water solubility is limited, as the structure includes hydrophobic components which hinder its ability to interact favorably with water molecules.
  • Temperature Dependency: Solubility can also increase with temperature, allowing for better dissolution in hot solvent systems.

As a general rule, the presence of functional groups like amides and piperidines does lend some potential for interaction with polar solvents, but the predominant hydrophobic nature often leads to notable insolubility in water.

To summarize, we could say, "N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide is predominantly soluble in organic solvents, while its solubility in water is minimal due to its complex structure." This solubility profile is essential for applications in organic synthesis and in the development of pharmaceuticals, as it influences the delivery and efficacy of compounds in biological systems.

Interesting facts

Interesting Facts about N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide

N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide is a fascinating compound with various applications and characteristics that make it a topic of interest among chemists. Here are some notable aspects:

  • Pharmacological Potential: This compound has been explored for its pharmacological properties. Its unique molecular structure allows it to interact with biological targets, making it a candidate for further research in medicinal chemistry.
  • Structural Complexity: The presence of both a piperidine ring and a phenyl group contributes to the molecule's structural complexity. This combination can lead to interesting interactions and potentially unique reactivity in synthetic applications.
  • Synthesis: The synthesis of this compound involves several steps, including the formation of the piperidine moiety and the acetamide group. Understanding the synthetic route can provide insights into reaction mechanisms and the importance of functional group modifications.
  • Biological Relevance: Compounds like this one often play important roles in studying neurological systems due to their potential effects on neurotransmitter pathways. This relevance makes it a significant compound in neuropharmacology.
  • Research Interest: Given its potential applications, researchers are actively studying this compound to unlock its full potential. Understanding its behavior in biological systems can guide the design of new therapeutic agents.

As we continue to investigate compounds like N-[2-methyl-1-phenyl-2-(1-piperidyl)propylidene]acetamide, we broaden our understanding of chemical interactions and pave the way for innovative solutions in medicine and beyond.