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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O
CAS number
73-78-9
IUPAC name
N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride
State
State

At room temperature, lidocaine hydrochloride is a crystalline solid.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
270.80g/mol
Molar mass
270.7980g/mol
Density
1.0060g/cm3
Appearence

Lidocaine hydrochloride is typically a white or nearly white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride

N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride exhibits unique solubility characteristics that can greatly influence its application and use. When considering the solubility of this compound, it is important to take into account various factors:

  • Polarity: Due to the presence of the ammonium ion in the piperidine ring, the compound is likely to exhibit higher polarity, which may enhance its solubility in polar solvents, such as water.
  • Hydrogen Bonding: The functional groups present may facilitate hydrogen bonding, a crucial interaction that can also increase solubility in aqueous solutions.
  • Interaction with Ionic Species: As this is a chloride salt, it may dissolve readily in environments containing various salts and ions.

However, it is essential to note that the solubility of this compound can be influenced by:

  • Temperature: Generally, increasing temperature can enhance solubility.
  • pH Levels: Being a salt, changes in the pH may affect the dissociation of the chloride component, which in turn can alter solubility.

In conclusion, while extensive data on the solubility of N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride is limited, its structural attributes suggest a favorable solubility in polar solvents, making it suitable for a variety of applications.

Interesting facts

Interesting Facts about N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride

N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride, commonly known in the scientific community for its intriguing structural features, is a fascinating compound that plays a significant role in various fields of research.

Structural Insights

This compound boasts a complex molecular architecture that includes:

  • Piperidine Ring: A six-membered ring that enhances its basicity and allows for various interactions with biological targets.
  • Phenyl Group: This aromatic structure contributes to the compound's unique electronic properties and the potential for π-π stacking interactions.
  • Acetamide Functionality: Provides linked reactivity, enabling various transformations and biological activities.

Biological Relevance

Researchers have taken a keen interest in this compound due to its:

  • Potential as a pharmacological agent: Some derivatives exhibit promising activity in neuropharmacology.
  • Influence in studying neurotransmitter systems: Exploring its interactions can unveil mechanisms related to cognition and mood regulation.

Synthesis and Applications

The synthesis of N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride involves innovative techniques that showcase modern organic chemistry methodologies. Notably:

  • The synthesis typically employs multi-step reactions to assemble its structure carefully.
  • Its derivatives have potential applications in developing therapeutic agents, particularly in treating neurological disorders.

In essence, N-(2-methyl-1-phenyl-2-piperidin-1-ium-1-yl-propylidene)acetamide;chloride stands as a symbol of innovation and discovery in chemical research, highlighting the intersections of organic synthesis, biological activity, and pharmacological advancements.

Synonyms
N-(alpha-(1-Methyl-1-piperidinoethyl)benzylidene)acetamide monohydrochloride
16297-35-1
ACETAMIDE, N-(alpha-(1-METHYL-1-PIPERIDINOETHYL)BENZYLIDENE)-, MONOHYDROCHLORIDE