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N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide

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Identification
Molecular formula
C12H16N2O
CAS number
22926-63-6
IUPAC name
N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide
State
State
This compound is typically a solid at room temperature, appearing as a crystalline powder.
Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
332.00
Boiling point (Kelvin)
605.15
General information
Molecular weight
204.26g/mol
Molar mass
204.2620g/mol
Density
1.1500g/cm3
Appearence

The compound N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide is generally a solid at room temperature. It can appear as a white to off-white crystalline powder, depending on its purity and the specific synthesis method used. It has a typical odor of amides, which can be slightly fishy or musty.

Comment on solubility

Solubility of N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide

The solubility of N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide in various solvents can be influenced by several factors, including polarity, temperature, and the presence of functional groups. This compound features both an amide group and an isoquinoline structure, which can exhibit diverse solubility characteristics.

Key Points on Solubility:

  • Polar Solvents: It is likely to be soluble in polar protic solvents such as water and alcohols due to the presence of the amide group.
  • Non-Polar Solvents: Conversely, its solubility in non-polar solvents might be limited, as isoquinoline structures typically have lower polarity.
  • Temperature Effects: Increased temperature may enhance solubility in solid-state compounds, facilitating greater dissolution rates.
  • Concentration Factors: At high concentrations, saturation effects can limit further dissolution.

Understanding the solubility profile of this compound is key in applications such as drug formulation, where achieving the right solubility can greatly affect biological availability. Therefore, experimental solubility assessments are vital to draw precise conclusions on its behavior in various mediums.

Interesting facts

Exploring N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide

N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide is a fascinating compound, primarily known for its significance in medicinal chemistry. Below are some captivating aspects of this compound:

  • Chirality: The presence of multiple chiral centers in this compound allows for the existence of different stereoisomers. This plays a crucial role in its biological activity.
  • Pharmacological Potential: Compounds similar to N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide have been researched for their potential therapeutic effects, particularly in the context of neuroprotection and the treatment of neurological disorders.
  • Isoquinoline Derivatives: This compound is derived from isoquinoline, a structure that is significant in various biochemical pathways. Isoquinoline derivatives have been linked to several biological activities, including anticancer and antimicrobial properties.
  • Synthetic Versatility: The synthetic routes for this compound show its versatility, making it an interesting target for synthesis in a lab setting. Chemists often explore various reaction conditions to optimize yields and purities.
  • Research Horizons: As research in medicinal chemistry evolves, compounds like N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide could pave the way for new drugs that target complex diseases in more effective ways.

In summary, N-(2-methyl-3,4-dihydro-1H-isoquinolin-5-yl)acetamide stands as a remarkable compound in the realm of chemistry. Its unique structure and potential pharmacological applications make it worthy of further exploration and study. As researchers continue to delve into its properties, we may discover even more secrets held within this intriguing molecule.

Synonyms
27536-05-6
BRN 0478637
ACETAMIDE, N-(1,2,3,4-TETRAHYDRO-2-METHYLISOQUINOLIN-5-YL)-
Isoquinoline, 1,2,3,4-tetrahydro-5-acetamido-2-methyl-
DTXSID70181951
RefChem:314884
DTXCID10104442
N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)acetamide
SCHEMBL6784777
SCHEMBL9289909
QBSCJGYBESVOAA-UHFFFAOYSA-N
N-(1,2,3,4-tetrahydro-2-methyl-5-isoquinolinyl)-acetamide