Memantine | Solubility of Things

Identification

Molecular formula

C₁₂H₂₁NO

CAS number

41100-52-1

IUPAC name

N-(2-morpholinoethoxy)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-imine

State

Memantine, in its base form, is typically solid at room temperature, possessing a crystalline structure. The hydrochloride salt is also a solid.

Melting point (Celsius)

292.00

Melting point (Kelvin)

565.15

Boiling point (Celsius)

472.10

Boiling point (Kelvin)

745.25

General information

Molecular weight

215.31g/mol

Molar mass

215.2780g/mol

Density

1.1830g/cm³

Appearence

Memantine hydrochloride, the most common form of memantine, typically appears as a white or off-white crystalline powder. It may also be available in tablet form, which is generally white to off-white in color.

Comment on solubility

Solubility of N-(2-morpholinoethoxy)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-imine

The solubility of N-(2-morpholinoethoxy)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-imine can be influenced by several factors, including its molecular structure and the presence of functional groups. In general, solubility is a complex characteristic that can be analyzed as follows:

Polarity: Compounds with polar functional groups typically exhibit higher solubility in polar solvents (e.g., water), while non-polar compounds dissolve better in non-polar solvents (e.g., hexane).
Hydrogen Bonding: The ability of a compound to form hydrogen bonds can greatly enhance its solubility. The presence of morpholine in this compound suggests potential for hydrogen bonding, which may improve solubility in aqueous environments.
Hydrophobic vs. Hydrophilic Balance: Analyzing the hydrophobic (water-repelling) and hydrophilic (water-attracting) portions of the molecule can provide insight into overall solubility.
Temperature Effects: Increasing temperature generally improves solubility for many organic compounds, making it essential to consider temperature conditions when discussing solubility.

In conclusion, understanding the solubility of this complex compound involves examining its molecular characteristics and how they interact with different solvents. As stated, "Like dissolves like," meaning that the solubility is heavily dependent on the nature of both the solute and the solvent. Therefore, empirical testing under various conditions is essential for definitive solubility data.

Interesting facts

Interesting Facts About N-(2-morpholinoethoxy)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-imine

This unique compound, N-(2-morpholinoethoxy)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-imine, holds a fascinating position in the world of organic chemistry due to its intricate molecular structure and potential applications. Here are some compelling insights about this compound:

Structural Complexity: The molecule features a tricyclic system, which not only contributes to its stability but also to its reactivity. The presence of multiple double bonds within the rings introduces interesting reactivity patterns.
Functional Group Diversity: The morpholino group plays a crucial role in enhancing the solubility and biological activity of the compound. This group is known for its ability to act as a nucleophile in various chemical reactions.
Potential Applications: Due to its unique structural features, derivatives of this compound may find utility in medicinal chemistry, particularly in the development of new pharmaceuticals targeting complex biological pathways.
Research Significance: The compound can serve as a model for studying reaction mechanisms involving polyenes and imines, providing insights into their behavior and interaction with different substrates.
Cyclic Compounds: The cyclic arrangement of atoms often imparts specific electronic and steric properties, making this compound a valuable target for synthesis in advanced materials science.

Researchers are keen on exploring compounds like N-(2-morpholinoethoxy)tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-imine, as they hold *the key to unlocking new scientific frontiers*. As they delve deeper into its potential, the possibilities for innovation seem boundless.