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N-(2-nitrophenyl)acetamide

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Identification
Molecular formula
C8H8N2O3
CAS number
552-89-6
IUPAC name
N-(2-nitrophenyl)acetamide
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
281.00
Boiling point (Kelvin)
554.15
General information
Molecular weight
180.16g/mol
Molar mass
180.1570g/mol
Density
1.3940g/cm3
Appearence

N-(2-nitrophenyl)acetamide appears as a crystalline solid that is typically pale yellow in color. The compound is usually available in powdered form or as crystalline pieces.

Comment on solubility

Solubility of N-(2-nitrophenyl)acetamide

N-(2-nitrophenyl)acetamide, a chemical compound with the formula C9H10N2O3, exhibits notable solubility characteristics that are important to understand in both laboratory and industrial settings.

The solubility of this compound can be influenced by several factors, including:

  • Polarity: N-(2-nitrophenyl)acetamide contains polar functional groups, which typically enhance solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of amide groups allows for potential hydrogen bonding, further aiding in solubilization.
  • Temperature: As is common with many organic compounds, increased temperature can lead to greater solubility as kinetic energy overcomes intermolecular forces.

Generally, N-(2-nitrophenyl)acetamide is expected to be moderately soluble in water but may also dissolve well in organic solvents such as ethanol and acetone. It is advisable to consult relevant solubility data for precise applications.

In conclusion, the solubility of N-(2-nitrophenyl)acetamide is a crucial factor that affects its use in various chemical processes, and understanding these solubility dynamics can enhance its practical applications.

Interesting facts

Exploring N-(2-nitrophenyl)acetamide

N-(2-nitrophenyl)acetamide is an intriguing compound that showcases the intersection of organic chemistry and functional group reactivity. This compound consists of an acetamide group connected to a nitrophenyl moiety, creating a unique structure that is both interesting and useful.

Key Characteristics

  • Applications in Research: N-(2-nitrophenyl)acetamide has significance in pharmaceutical chemistry, particularly in the synthesis of various biologically active compounds. It is often employed as an intermediate in drug discovery.
  • Reactivity: This compound can undergo various chemical reactions, including nucleophilic substitutions and electrophilic aromatic substitutions, making it versatile in laboratory settings.
  • Analytical Uses: It is also used in analytical chemistry as a reagent due to its ability to form colored complexes, which can be used for quantitative analysis.

Chemical Behavior

One of the most fascinating aspects of N-(2-nitrophenyl)acetamide is its electronic properties. The presence of the nitro group significantly influences the electron density of the aromatic ring, making it more susceptible to electrophilic attack. This can lead to:

  • Increased reactivity in substitution reactions
  • Distinctive spectral properties that can be utilized in various characterization techniques, such as IR and NMR spectroscopy

Safety Considerations

As with many organic compounds, it is crucial to handle N-(2-nitrophenyl)acetamide with care. It may pose risks if inhaled or ingested, and appropriate laboratory safety protocols should always be followed to ensure safe handling. This includes:

  • Wearing protective gear, such as gloves and goggles
  • Using a fume hood when conducting reactions that may release vapors

In conclusion, N-(2-nitrophenyl)acetamide is not only an essential compound in synthetic chemistry but also a unique example of how structure relates to reactivity. Its applications in research and industry continue to be of great interest to chemists around the world. Understanding this compound opens doors to new discoveries and enhances our grasp of organic synthesis!

Synonyms
N-(2-Nitrophenyl)acetamide
2'-NITROACETANILIDE
2-Nitroacetanilide
o-Nitroacetanilide
Acetamide, N-(2-nitrophenyl)-
UNII-Q4KJC83992
NSC 1313
NSC-1313
EINECS 209-009-6
AI3-08843
N-ACETYL-O-NITROANILINE
O-NITROACETANILIDE [MI]
DTXSID4060282
DTXCID6041846
209-009-6
bunfnrvlmkhkit-uhfffaoysa-n
552-32-9
Acetanilide, 2'-nitro-
MFCD00016991
Q4KJC83992
N1-(2-nitrophenyl)acetamide
o-nitroacetoanilide
o-Acetylaminonitrobenzene
N-acetyl-2-nitroaniline
Maybridge1_000147
MixCom1_000279
SCHEMBL733777
N-(2-Nitrophenyl)acetamide #
CHEMBL3601315
NSC1313
BBL000675
STK366846
AKOS002260841
FN71139
SY076168
VS-00663
CS-0137350
N0107
NS00033266
EN300-137309
S10880
Q27286995