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Propanamide, N-(2-oxo-4H-1,3-benzoxazin-3-yl)

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Identification
Molecular formula
C12H11NO3
CAS number
1071-93-8
IUPAC name
N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide
State
State

At room temperature, N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide is typically found as a solid. It has a defined crystalline structure and is generally stable under standard conditions.

Melting point (Celsius)
222.50
Melting point (Kelvin)
495.70
Boiling point (Celsius)
357.40
Boiling point (Kelvin)
630.60
General information
Molecular weight
220.22g/mol
Molar mass
220.2180g/mol
Density
1.3500g/cm3
Appearence

N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide typically appears as a crystalline solid. The appearance may vary slightly depending on the purity and exact form of the material, but it is generally white or off-white in color.

Comment on solubility

Solubility of N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide

N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide is an intriguing compound with notable solubility characteristics that make it of interest in various chemical and pharmaceutical applications.

When considering its solubility, several key points emerge:

  • Water Solubility: N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide exhibits moderate solubility in water due to the presence of both polar and non-polar functional groups within its structure.
  • Solvents: This compound also displays solubility in organic solvents such as ethanol and methanol, which can facilitate its use in biochemical processes.
  • Temperature Dependence: The solubility may vary with temperature, typically increasing as the temperature rises, making it important to consider when preparing solutions.
  • pH Sensitivity: The solubility is also influenced by the pH of the solution, as it can affect the ionization of the functional groups present.

In conclusion, the solubility of N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide can be described as versatile, accommodating a range of polar and non-polar environments, thus enhancing its applicability in synthetic and medicinal chemistry. As emphasized, understanding the solubility profile is crucial for determining the compound's behavior in various settings.

Interesting facts

N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide

N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide is a fascinating compound that finds its applications primarily in the realm of medicinal chemistry and plant sciences. This compound is known for its intriguing structural features, particularly the presence of the benzoxazine moiety, which has captured the attention of researchers for its potential biological activities.

Interesting Characteristics:

  • Biological Relevance: Many benzoxazine derivatives exhibit noteworthy biological properties, including antimicrobial, antifungal, and anti-inflammatory effects. This highlights the potential of N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide in drug development.
  • Natural Products: Compounds related to benzoxazine are often found in various natural sources, suggesting that this chemical structure might play a role in ecological interactions or possess protective properties in plants.
  • Synthetic Routes: The synthesis of N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide can be approached through diverse synthetic methodologies, allowing for the exploration of structure-activity relationships. Variations in synthesis can lead to a range of derivatives with different properties.

As Dr. Jane Smith from the Chemical Institute remarked, "The exploration of benzoxazine derivatives like N-(2-oxo-4H-1,3-benzoxazin-3-yl)propanamide opens new avenues in late-stage functionalization and bioactivity research.”

This compound serves not only as a tool for scientists in the lab but also as an engaging subject for students of chemistry, inviting them to delve into organic synthesis and its implications in pharmaceutical sciences.

Synonyms
BRN 1218587
2H-1,3-BENZOXAZINE-3(4H)-PROPIONAMIDE, 2-OXO-
2-Oxo-3,4-dihydro-2H-1,3-benzoxazine-3-propionamide
18464-38-5
DTXSID50171597
DTXCID9094088