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Isoniazid

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Identification
Molecular formula
C6H7N3O
CAS number
54-85-3
IUPAC name
N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide
State
State

At room temperature, Isoniazid is in a solid state.

Melting point (Celsius)
171.00
Melting point (Kelvin)
444.00
Boiling point (Celsius)
251.00
Boiling point (Kelvin)
524.00
General information
Molecular weight
137.14g/mol
Molar mass
137.1390g/mol
Density
1.4000g/cm3
Appearence

Isoniazid typically appears as a white crystalline powder.

Comment on solubility

Solubility of N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide

The solubility of N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide can be characterized by several key factors:

  • Polarity: This compound exhibits significant polarity due to the presence of nitrogen and carbonyl groups. As a result, it may show moderate solubility in polar solvents such as water or methanol.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvation molecules can enhance its solubility, particularly in aqueous environments.
  • Concentration Effects: As with many organic compounds, solubility may be concentration-dependent, with higher concentrations potentially leading to precipitation.

Quotes from solubility rules: "Like dissolves like." Therefore, its solubility could be more favorable in solvents that share similar functional groups, such as alcohols or amines, rather than in nonpolar solvents.

Factors influencing solubility:

  1. Temperature: Increased temperature often enhances solubility.
  2. pH Level: The pH of the solvent can affect the ionization state of the compound, impacting solubility.
  3. Presence of Other Solutes: The presence of salts or other compounds can lead to competition for solvation, thereby affecting overall solubility.

In summary, while the solubility of N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide may not be extraordinary, it is influenced by several structural and environmental factors that merit careful consideration in research and practical applications.

Interesting facts

Interesting Facts about N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide

N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide is a fascinating chemical compound that draws the attention of researchers due to its unique structure and potential applications. Here are some key insights:

  • Structural Complexity: The compound features multiple functional groups, including hydrazine and pyridine derivatives, which contribute to its intriguing reactivity and properties.
  • Potential Biological Activity: Many compounds that incorporate hydrazine and pyridine moieties have been investigated for their biological activities, including antitumor and antimicrobial properties.
  • Coordination Chemistry: Due to the presence of nitrogen atoms in both the hydrazino and pyridine groups, the compound may exhibit interesting coordination chemistry, potentially forming stable complexes with metal ions.
  • Research Trends: The exploration of hydrazone derivatives such as this compound has surged due to their versatility in designing novel pharmaceuticals and agrochemicals.
  • Versatile Applications: Beyond pharmaceuticals, compounds with similar structures are often utilized in the fields of materials science and catalysis.

Understanding such compounds enables scientists to innovate and discover new applications that can profoundly impact various industries. As chemistry continues to evolve, the study of complex molecules like N'-[[2-(pyridine-4-carbonyl)hydrazino]methyl]pyridine-4-carbohydrazide holds promise for unlocking further scientific advancements.

Synonyms
Metazide
Methazide
1707-15-9
Metazide [INN]
Metazida
Methazidum
Isonicotinic acid 2,2'-methylenedihydrazide
Metazidum [Latin]
N,N-Methylenebisisoniazid
Metazida [Spanish]
Metazidum
Bis(isonicotinylhydrazo)methane
Metazidum [INN-Latin]
Metazida [INN-Spanish]
Ro 2-4969
NSL1M7IFYP
NSC 39302
NSC-39302
BRN 0294524
DTXSID9046239
1,1'-Methylenebis(2-isonicotinylhydrazine)
METAZIDE [WHO-DD]
4-Pyridinecarboxylic acid, 2,2'-methylenedihydrazide
DTXCID7026239
4-22-00-00562 (Beilstein Handbook Reference)
Metazidum (Latin)
Metazidum (INN-Latin)
Metazida (INN-Spanish)
4-Pyridinecarboxylic acid, 2,2'-methylenedihydrazide (9CI)
654-507-2
Metazid
Methazid
N'-[[2-(pyridine-4-carbonyl)hydrazinyl]methyl]pyridine-4-carbohydrazide
NCGC00160572-01
UNII-NSL1M7IFYP
SCHEMBL2109857
CHEMBL1526558
NSC39302
Tox21_111909
Ro 24969
AKOS024332405
Isonicotinic acid,2'-methylenedihydrazide
CAS-1707-15-9
NS00126492
4-Pyridinecarboxylic acid,2'-methylenedihydrazide
SR-01000945017
SR-01000945017-1
Q27285034