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N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide

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Identification
Molecular formula
C12H10N4OS
CAS number
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IUPAC name
N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide
State
State
State: Solid at room temperature, typically found as a crystalline powder. The compound is stable under normal conditions, but it's advised to store it in a cool, dry place. It does not change state under ambient conditions.
Melting point (Celsius)
220.00
Melting point (Kelvin)
493.00
Boiling point (Celsius)
598.00
Boiling point (Kelvin)
871.00
General information
Molecular weight
244.30g/mol
Molar mass
244.2990g/mol
Density
1.3980g/cm3
Appearence
This compound typically appears as a powdery solid, often white to slightly off-white in color. The exact appearance might vary slightly depending on the method of synthesis and any impurities present. Handling: Appropriate measures should be taken during handling to prevent exposure or inhalation, such as working in a well-ventilated area or under a fume hood.
Comment on solubility

Solubility of N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide

The solubility of N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide can be influenced by various factors, including the presence of functional groups and the molecular structure. Generally, compounds that contain both polar and nonpolar functional groups exhibit unique solubility characteristics.

For N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide, consider the following:

  • Polar Characteristics: The presence of the acetamide group contributes to some polar interactions, enhancing solubility in polar solvents like water.
  • Nonpolar Elements: The thiazole and benzimidazole rings can introduce nonpolar characteristics, which may reduce solubility in highly polar solvents.
  • Temperature Effects: Increased temperature can often improve solubility for many compounds, leading to greater dissolution in solvents.

In summary, the solubility of N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide is likely to be moderate in water and higher in organic solvents, depending on the concentration and specific solvent interactions. As one expert aptly puts it, “Understanding the solubility of a compound is crucial for anticipating its behavior in various environments.”

More specific solubility data may be obtained through experimental studies to assess its behavior in practical applications.

Interesting facts

Interesting Facts about N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide

N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide is a fascinating compound that has piqued the interest of researchers due to its diverse applications and unique structural properties. Here are some compelling facts about this intriguing molecule:

  • Pharmacological Potential: This compound falls within the category of benzimidazole derivatives, which are known for their broad spectrum of biological activities. They have been studied for their potential as anti-cancer, anti-inflammatory, and anti-viral agents.
  • Thiazole Ring: The presence of a thiazole moiety in its structure contributes to its reactivity and biological properties. Thiazoles are known for imparting *electrophilic* characteristics that enhance the compound’s interaction with biological systems.
  • Synthesis Interest: The synthetic methodologies employed in the preparation of this compound often involve multi-step processes, showcasing creative chemical ingenuity. Researchers often explore various routes to optimize yields and target specific action mechanisms.
  • Research Applications: The compound serves as an interesting subject for ongoing research in medicinal chemistry, as scientists aim to unravel its mechanisms of action. This may pave the way for new therapeutic agents.
  • Interdisciplinary Appeal: Due to its unique properties, this compound attracts interest not only from chemists but also from biologists and pharmacologists, culminating in collaborative research across disciplines.

As stated by one prominent researcher, "Innovation in compound design is paramount to addressing the evolving challenges in healthcare." This compound exemplifies how careful structural considerations can lead to significant advancements in therapeutic applications. The continual study of N-(2-thiazol-4-yl-3H-benzimidazol-5-yl)acetamide is likely to yield new insights, making it a key player in the realm of medicinal chemistry.

Synonyms
27192-25-2
ACETAMIDE, N-(2-(4-THIAZOLYL)-5-BENZIMIDAZOLYL)-
TBDZ.NH.Ac
N-(2-(Thiazol-4-yl)-1H-benzo[d]imidazol-6-yl)acetamide
N-(2-(4-Thiazolyl)-5-benzimidazolyl)acetamide
Acetamide, N-(2-4-thiazolyl)-5-(benzimidazolyl)-
DTXSID40181660