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N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide

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Identification
Molecular formula
C9H8Cl2FNO2
CAS number
Not Available
IUPAC name
N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide
State
State

At room temperature, this compound is in a solid state, often found as a crystalline powder. It is stable under normal conditions but may require specific storage conditions to prevent degradation, such as keeping it in a dry, cool place away from light.

Melting point (Celsius)
149.50
Melting point (Kelvin)
422.70
Boiling point (Celsius)
315.20
Boiling point (Kelvin)
588.30
General information
Molecular weight
264.06g/mol
Molar mass
264.0560g/mol
Density
1.5120g/cm3
Appearence

The compound is typically found as a solid crystalline substance, often appearing white or off-white in color. It does not have a distinct odor and may be obtained in powdered form as well.

Comment on solubility

Solubility of N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide

N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide exhibits moderate solubility in various organic solvents and limited solubility in water. Understanding its solubility characteristics is crucial for its application in various fields. Here are some key points about its solubility:

  • Solvents: This compound tends to dissolve well in polar organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Aqueous ethanol
    • Acetone
  • Water Solubility: It is sparingly soluble in water due to:
    • The presence of bulky aromatic and halogen substituents, which hinder interactions with water molecules.
    • Hydrophobic regions that repel water, lowering the overall solubility.

In summary, while N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide shows a preference for organic solvents, its limited water solubility can impact its behavior in biological and environmental contexts. Understanding these solubility properties is vital for utilizing this compound effectively.

Interesting facts

Interesting Facts about N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide

N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide is a fascinating compound that presents intriguing possibilities in various fields of chemistry, especially in medicinal chemistry and agrochemicals. Here are some key points to note:

  • Biological Activity: This compound's unique structure suggests potential biological activities, which can be of interest in drug design. Its dichloro and fluoro substituents may enhance its ability to interact with biological targets.
  • Structural Features: The presence of both hydroxy and amide functional groups in its structure is particularly noteworthy. This combination can impart unique properties that influence solubility and binding interactions in biological systems.
  • Versatile Applications: Compounds like this one are often explored for their ability to act as herbicides or pesticides, given that many agrochemicals incorporate halogen atoms to increase potency and specificity.
  • Research Interest: The synthetic strategies involved in creating this compound are also interesting. The incorporation of halogens typically poses challenges during synthesis, making its preparation a valuable topic for chemical research.
  • Environmental Considerations: With increasing regulation around halogenated compounds, understanding the environmental impact of compounds like this one is crucial. Research into their degradation pathways can yield insights into safe usage.

In summary, N-(2,2-dichloro-1-hydroxy-ethyl)-4-fluoro-benzamide stands at the intersection of synthetic organic chemistry and potential practical applications. As with many compounds in the field, ongoing research may unveil even more about its utility and implications for human health and the environment.

Synonyms
N-(2,2-dichloro-1-hydroxyethyl)-4-fluorobenzamide
1208-18-0
BRN 1971871
Dichloroacetaldehyde p-fluorobenzamide
(N-(2,2'-Dichloro-1-hydroxy)ethyl)-p-fluorobenzamide
BENZAMIDE, (N-(2,2'-DICHLORO-1-HYDROXY)ETHYL)-p-FLUORO-
DTXSID80923561