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Trichlorfon

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Identification
Molecular formula
C4Cl3O4P
CAS number
52-68-6
IUPAC name
N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide
State
State

At room temperature, trichlorfon is in a solid state, appearing typically as a crystalline powder.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
120.00
Boiling point (Kelvin)
393.15
General information
Molecular weight
257.50g/mol
Molar mass
257.4950g/mol
Density
1.7264g/cm3
Appearence

Trichlorfon typically appears as a colorless crystalline solid. In its pure form, it may also be found as white crystals or powder. It is commonly used in agriculture and certain industrial applications.

Comment on solubility

Solubility of N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide

The solubility of N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide can be complex due to its unique chemical structure. Factors influencing its solubility include:

  • Polarity: The presence of multiple chlorine atoms contributes to the compound's polarity, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: The amide functional group (-C(O)NH-) can engage in hydrogen bonding, potentially increasing solubility in water and other hydrogen-bonding solvents.
  • Hydrophobic Interactions: The bulky trichloro ethyl substituents may lead to hydrophobic characteristics that can limit solubility in aqueous environments.

In general, this compound is expected to exhibit:

  1. Higher solubility in polar solvents like methanol or dimethyl sulfoxide (DMSO).
  2. Limited solubility in non-polar solvents due to its heavier chlorinated structure.
  3. Variable behavior in mixed solvents, where both polar and non-polar characteristics can influence solubilization.

Ultimately, routine experimentation is recommended to determine precise solubility properties, as they can differ based on concentration and temperature conditions, along with other solvent interactions. Always consult specific solubility data or perform empirical studies for accurate assessments.

Interesting facts

Interesting Facts about N-[2,2,2-Trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide

N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide is a fascinating compound with a variety of notable characteristics that pique the interest of both scientists and chemistry students alike. Here are some compelling insights:

  • Complex Structure: This compound features a unique molecular architecture, incorporating multiple functional groups, including formamide and piperazine. This complexity can lead to interesting chemical behavior and reactivity.
  • Halogen Impact: The presence of 2,2,2-trichloro groups suggests a potential for enhanced biological activity and may influence the compound's pharmacological properties. Halogens often confer interesting electronic characteristics to neighboring atoms.
  • Potential Applications: Compounds of this nature may be explored for use in pharmaceuticals, especially in the development of agents targeting specific biological pathways or functions due to their intricate design.
  • Synthetic Relevance: The synthesis of such complex molecules often requires innovative synthetic strategies, making this compound a subject of interest for organic chemists and a challenging endeavor for students in labs.
  • Research Opportunities: Investigating the biological activity of this compound can open doors to understanding structure-activity relationships, ultimately contributing to advancements in medicinal chemistry.
  • Environmental Considerations: Given its chlorinated nature, the environmental impact of this compound, particularly its stability and degradation products, can be a crucial area of study in the context of chemical safety and regulation.

As a result of these factors, N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide represents an intriguing intersection of synthetic chemistry, pharmacology, and environmental science, making it a valuable topic for deeper exploration.

Synonyms
TRIFORINE
26644-46-2
Saprol
Funginex
Biformylchlorazin
CELA 50
Biformychlorazin
CW 524
CELA W 524
DTXSID5032654
CA 70203
1,4-Bis(2,2,2-trichloro-1-formamidoethyl)piperazine
W 524
N,N'-Bis(1-formamido-2,2,2-trichloroethyl)piperazine
N1A4W8U0HH
CME 74770
CHEBI:9715
1,4-Bis(1-formamido-2,2,2-trichloroethyl)piperazine
Formamide, N,N'-(1,4-piperazinediylbis(2,2,2-trichloroethylidene))bis-
NSC-263493
N,N'-(1,4-Piperazinediylbis(2,2,2-trichloroethylidene))bisformamide
N,N'-(Piperazine-1,4-diylbis((trichloromethyl)methylene))diformamide
DTXCID3012654
RefChem:191617
247-872-0
Triforin
1,4-bis(1-formamido-2,2,2-trichloroethyl)-piperazine
C10H14Cl6N4O2
N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamidoethyl)piperazin-1-yl]ethyl]formamide
Caswell No. 890AA
N-[2,2,2-trichloro-1-[4-(2,2,2-trichloro-1-formamido-ethyl)piperazin-1-yl]ethyl]formamide
Triforine [ISO]
Triforine [ANSI:BSI:ISO]
HSDB 6743
EINECS 247-872-0
UNII-N1A4W8U0HH
EPA Pesticide Chemical Code 107901
NSC 263493
BRN 0626358
TRIFORINE [MI]
TRIFORINE [HSDB]
N,N'-(Piperazinediylbis(2,2,2-trichloroethylidene)) bis(formamide)
SCHEMBL23278
5-23-01-00042 (Beilstein Handbook Reference)
CELA-W 524
CHEMBL453418
orb1705878
1,2,2-trichloroethyl)piperazine
N,2,2-trichloroethyl)piperazine
Piperazine, 1,4-bis(1-formamido-2,2,2-trichloroethyl)-
HY-B2056
MSK21242
Tox21_302268
MFCD00055521
N,N'-(1,4-Piperazinediylbis(2,2,2-trichloroethylidene)) bisformamide
NSC263493
AKOS040744482
N,N'-(1,4-Piperazinediyl-bis(2,2,2-trichloroethyldene))bis(formamide)
NCGC00164301-01
NCGC00255254-01
CA 73021
CAS-26644-46-2
CS-0014149
NS00009786
Triforin, PESTANAL(R), analytical standard
644T462
Q2453158
Piperazine,4-bis(1-formamido-2,2,2-trichloroethyl)-
1, 4-Bis(1-formamido-2,2,2-trichloroethyl)piperazine
N,4-Piperazinediylbis(2,2,2-trichloroethylidene)]bis(formamide)
Formamide,N'-[1,4-piperazinediylbis(2,2,2-trichloroethylidene)]bis-
N,N'-[piperazine-1,4-diylbis(2,2,2-trichloroethane-1,1-diyl)]diformamide
N,N'-(1,4-PIPERAZINDIYLBIS(2,2,2-TRICHLOR-1,1-ETHANDIYL))DIFORMAMID
N,N'-(PIPERAZIN-1,4-DIYLBIS(2,2,2-TRICHLORETHAN-1,1-DIYL))DIFORMAMID