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N-isobutyryl-2-(2,3-dihydro-1,4-benzodioxin-3-yl)ethylamine

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Identification
Molecular formula
C13H19NO2
CAS number
52939-12-1
IUPAC name
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine
State
State

At room temperature, the compound is a liquid.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.15
General information
Molecular weight
221.29g/mol
Molar mass
221.2880g/mol
Density
1.0430g/cm3
Appearence

The compound N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine is typically a colorless to pale yellow liquid. It is often clear and has low to moderate viscosity.

Comment on solubility

Solubility of N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine

N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine displays interesting solubility characteristics that are crucial for its applications in various chemical reactions and formulations. Understanding its solubility can be likened to deciphering a puzzle—each piece influences its behavior in different environments.

Water Solubility

This compound is largely insoluble in water due to the presence of the hydrophobic benzodioxin moiety. The bulky aromatic structure tends to resist interactions with polar water molecules, leading to limited solvation.

Solvent Compatibility

Interestingly, N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine shows favorable solubility in various organic solvents. Some key solubilizing agents include:

  • Alcohols (e.g., ethanol, methanol): Enhanced solubility due to hydrogen bonding capabilities.
  • Aromatic hydrocarbons (e.g., toluene, xylene): The compatibility with similar structures aids solvation.
  • Dimethyl sulfoxide (DMSO): Exhibits good solubility, allowing for diverse chemical reactions.

Temperature Effect

The solubility of this compound, like many organic molecules, is also temperature-dependent. As temperature increases, the kinetics of dissolution increases, generally enhancing solubility in organic solvents.

Conclusion

In summary, while N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine may be insoluble in water, its compatibility with organic solvents opens up various possibilities for practical usage. Knowing the solubility profile allows chemists and researchers to optimize conditions for synthesis and application.

Interesting facts

Interesting Facts about N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine

N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine, often recognized for its complex structure, is a compound that straddles the realms of organic chemistry and pharmacology. Below are some intriguing aspects of this compound that may pique the interest of chemistry enthusiasts:

  • Structural Diversity: This compound exhibits a unique fusion of a benzodioxin moiety and an ethyl-ethanamine chain, which potentially augments its interactions with biological targets.
  • Biological Significance: The presence of the benzodioxin ring system is significant in medicinal chemistry as such scaffolds are often found in bioactive molecules, contributing to various pharmacological activities.
  • Synthetic Pathways: The synthesis of this compound involves intricate multi-step reactions, which presents a fascinating challenge for chemists aiming to optimize yield and purity.
  • Potential Applications: Compounds of this nature are being explored for their roles in the development of new drugs, particularly targeting neurotransmitter systems and neurological disorders.
  • Research Focus: Studies surrounding this compound may lead to insights into its mechanisms of action, providing valuable data for future investigations into similar chemical entities.

As expressed by pioneers in the field, "The diversity of chemical structures leads to a broader understanding of their applications and interactions." The exploration of N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-N-ethyl-ethanamine not only enriches our knowledge of chemistry but also underscores the potential for innovation within drug discovery and development.

Synonyms
Prosympal
Fourneau 883
Diethylaminomethyl-2-benzodioxan
952-37-4
NSC 42174
BRN 0190980
1,4-Benzodioxan, 2-(diethylaminomethyl)-
N,N-Diethyl-2,3-dihydro-1,4-benzodioxin-2-methanamine
883 F
1,4-Benzodioxin-2-methanamine, N,N-diethyl-2,3-dihydro-
5-19-08-00403 (Beilstein Handbook Reference)
1,4-BENZODIOXAN-2-METHYLAMINE, N,N-DIETHYL-
2-(diethylaminomethyl)-1,4-benzodioxane
1,4-Benzodioxin-2-methanamine, N,N-diethyl-2,3-dihydro-(9CI)
1, 2-(diethylaminomethyl)-
CHEMBL52269
1, N,N-diethyl-2,3-dihydro-
DTXSID101214601
NSC42174
NSC-42174
2-(diethylamino-methyl)-1,4-benzodioxane
Q3407877