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N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine

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Identification
Molecular formula
C12H17NO
CAS number
132067-45-1
IUPAC name
N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine
State
State

At room temperature, N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine is typically found in a solid state. This compound is stable under normal conditions and does not volatilize easily, owing to its relatively higher melting point compared to other amines without the aromatic or heterocyclic backbone.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
177.27g/mol
Molar mass
177.2400g/mol
Density
1.0710g/cm3
Appearence

The compound N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine appears as a colorless solid in pure form. It can also present as a crystalline powder, often characterized by its unique structural motif including the benzofuran moiety, which can affect its color slightly depending on purity and form. When impure, it might appear in slightly off-white hues.

Comment on solubility

Solubility of N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine

The solubility characteristics of N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine are influenced by its unique molecular structure and functional groups. This compound can be classified as a relatively hydrophobic amine, resulting in varying solubility profiles depending on the solvent used.

Key Points on Solubility:

  • Solvent Dependence: Most organic compounds, especially those with aromatic components, display greater solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Hydrophobic Nature: The presence of the benzofuran moiety suggests limited solubility in water, a characteristic typical of many hydrophobic compounds.
  • Potential for Salt Formation: If the compound is converted into a salt form (e.g., hydrochloride), its solubility in water can significantly increase, enhancing its bioavailability.

In summary, while N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine may exhibit low solubility in polar solvents like water, it is expected to dissolve effectively in non-polar or less polar organic solvents. This property underscores the importance of considering specific solvent systems when evaluating the solubility and potential applications of this compound.

Interesting facts

Interesting Facts about N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine

N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine, often referred to by its simplified name, is a fascinating compound in the realm of organic chemistry. Here are some intriguing aspects that highlight its significance:

  • Structural Diversity: This compound features a unique molecular structure that includes a benzofuran moiety. The presence of this heterocyclic ring contributes to its potential reactivity and biological activity.
  • Potential Pharmacological Applications: Variations of aminated compounds similar to this one have been explored for medicinal purposes, particularly in psychopharmacology. Researchers are investigating compounds with similar structures for their potential to modulate neurotransmitter systems.
  • Importance in Synthesis: The synthesis of N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine could be of interest in drug development. Its synthesis may provide insights into creating more complex and biologically active molecules.
  • Analytical Methods: Studying this compound presents challenges and opportunities for analytical chemists. Techniques like NMR, FTIR, and mass spectrometry are essential tools for characterizing such complex molecules.
  • Sustainability Considerations: The exploration of organic compounds like this one can lead to more sustainable practices in pharmaceuticals. Finding ways to synthesize and utilize these compounds efficiently is an area of ongoing research.

In conclusion, N-(2,3-dihydrobenzofuran-2-ylmethyl)propan-2-amine is more than just a chemical formula; it is a **gateway** into the world of organic synthesis, medicinal chemistry, and potential applications that can benefit society. Engaging with such compounds encourages a broader understanding of chemical interactions and their implications in various fields.

Synonyms
2,3-Dihydro-N-(1-methylethyl)-2-benzofuranmethanamine
21130-03-0
DTXSID801212951