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Memantine

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Identification
Molecular formula
C12H21ClN
CAS number
41100-52-1
IUPAC name
N-[(2,4-dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine
State
State

At room temperature, memantine exists as a solid. It is usually handled in powdered form for pharmaceutical use.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
215.76g/mol
Molar mass
215.2920g/mol
Density
1.0365g/cm3
Appearence

Memantine is typically encountered as a white or off-white crystalline powder. Its crystalline nature can give it a slightly shiny appearance under light. In its pure form, it is devoid of color and is not known to have any significant odor.

Comment on solubility

Solubility of N-[(2,4-dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine

N-[(2,4-dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine is an intriguing compound with a somewhat complex solubility profile. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the 2,4-dichlorophenyl group suggests a degree of hydrophobic characteristic, potentially limiting solubility in polar solvents.
  • Functional Groups: The amine functional group might interact with polar solvents, leading to improved solubility in certain organic solvents.
  • Temperature: As with many organic compounds, solubility often increases with temperature, which can facilitate the dissolution process.
  • pH Dependence: The solubility of amine compounds can also vary with pH, potentially enhancing solubility in acidic solutions where the amine group may become protonated.

Experimental solubility data indicates that this compound may show:

  1. Limited solubility in water.
  2. Better solubility in non-polar organic solvents like hexane or dichloromethane.

In summary, the solubility of N-[(2,4-dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine is a delicate balance between its structural characteristics and the solvent environment. As noted, its solubility behaviors may offer intriguing insights into its potential applications in various fields.

Interesting facts

N-[(2,4-Dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine

This unique compound is primarily known for its prominent role in the field of synthetic chemistry. Here are some interesting aspects that reveal its significance:

  • Pharmaceutical Applications: This compound has been explored for its potential therapeutic uses, particularly in the treatment of various neurological disorders. Its structural components may interact effectively with neurotransmitter systems.

  • Synthetic Versatility: The architecture of the norbornane backbone provides an exceptional platform for further chemical modifications. This makes it a valuable synthetic intermediate in organic chemistry.

  • Environmental Considerations: With the incorporation of chlorinated phenyl groups, studies often investigate the environmental impact and degradation pathways of such compounds. Understanding these pathways is crucial for developing safer chemical alternatives.

  • Structure-Activity Relationship (SAR): The specific arrangement of atoms and functional groups leads to unique biological activities. Researchers often focus on SAR studies to optimize the efficacy of similar compounds.

  • Analytical Insights: Compounds like N-[(2,4-dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine also pose analytical challenges. Techniques like NMR and mass spectrometry are commonly employed to ascertain the purity and identity of such complex molecules.

In summary, the exploration of N-[(2,4-dichlorophenyl)methyl]-1,7,7-trimethyl-norbornan-2-amine is a demonstration of how intricate chemistry can yield significant applications across various fields. Its unique structure not only invites curiosity but also encourages ongoing research and discovery.

Synonyms
AKOS009006443