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Acetanilide

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Identification
Molecular formula
C10H13NO
CAS number
103-84-4
IUPAC name
N-(2,4-dimethylphenyl)acetamide
State
State

At room temperature, acetanilide is in a solid state, presenting itself as a white, crystalline substance.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
304.00
Boiling point (Kelvin)
577.15
General information
Molecular weight
149.19g/mol
Molar mass
149.1870g/mol
Density
1.0804g/cm3
Appearence

Acetanilide typically appears as a white, crystalline solid. It has no distinctive odor and a grainy texture. Sometimes it may appear slightly off-white due to impurities, but pure acetanilide is distinctly white.

Comment on solubility

Solubility of N-(2,4-dimethylphenyl)acetamide

N-(2,4-dimethylphenyl)acetamide, with a chemical formula of C11H15NO, exhibits interesting solubility characteristics that are influenced by its molecular structure. Being an amide, it tends to show varying solubility in different solvents:

  • Polar solvents: N-(2,4-dimethylphenyl)acetamide is generally more soluble in polar solvents such as water and ethanol due to its ability to participate in hydrogen bonding.
  • Non-polar solvents: Contrarily, it may find limited solubility in non-polar solvents like hexane or benzene, owing to the hydrophobic nature of the phenyl group.
  • Temperature dependence: The solubility of this compound may increase with temperature, leading to a greater dissolution in solvents at higher temperatures.

It is essential to consider the interaction of N-(2,4-dimethylphenyl)acetamide with solvent molecules. As highlighted, the presence of functional groups such as the acetamide moiety can play a critical role in determining solubility. In summary, understanding the solubility of this compound can be distilled into two key points:

  1. Polar solvents enhance solubility.
  2. Non-polar solvents provide limited solubility.

These characteristics make N-(2,4-dimethylphenyl)acetamide a versatile compound in various chemical applications and experimental settings.

Interesting facts

Interesting Facts About N-(2,4-Dimethylphenyl)acetamide

N-(2,4-dimethylphenyl)acetamide is an intriguing compound with noteworthy qualities that make it significant in various fields. Here are some key highlights:

  • Pharmaceutical Relevance: This compound serves as an important precursor or intermediate in the synthesis of various pharmaceuticals. Compounds with amide functionalities often exhibit different biological activities, making them essential in drug development.
  • Industrial Utilization: Beyond pharmaceuticals, N-(2,4-dimethylphenyl)acetamide is incorporated into different industrial applications, including the synthesis of agrochemicals and specialty chemicals.
  • Unique Properties: The substitution of methyl groups at the 2 and 4 positions of the phenyl ring alters its electronic and steric properties, which can lead to intriguing reactivity patterns and interactions in chemical reactions.
  • Research Applications: This compound is often used as a model molecule in studies related to molecular interactions, helping researchers understand the effects of structural changes on chemical behavior.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This statement rings true for N-(2,4-dimethylphenyl)acetamide, contributing to a plethora of ideas in synthetic chemistry and beyond.

Overall, N-(2,4-dimethylphenyl)acetamide demonstrates the fascinating intersection of chemistry and practicality, inspiring further research and innovation in both academic and industrial sectors.

Synonyms
N-(2,4-Dimethylphenyl)acetamide
2',4'-Dimethylacetanilide
Acetamide, N-(2,4-dimethylphenyl)-
2,4-Dimethylacetanilide
2',4'-Acetoxylidine
2',4'-ACETOXYLIDIDE
N-Acetyl-2,4-xylidine
Acetanilide, 2',4'-dimethyl-
NSC 37567
N-Acetoxy-2,4-dimethylaniline
EINECS 218-088-6
UNII-3U0W52HZ1H
BRN 2690429
3U0W52HZ1H
DTXSID0044868
AI3-21210
NSC-37567
DTXCID8024868
4-12-00-02548 (Beilstein Handbook Reference)
MBR-22441
inchi=1/c10h13no/c1-7-4-5-10(6-8(7)2)11-9(3)12/h4-6h,1-3h3,(h,11,12)
pjeiibxjudoman-uhfffaoysa-n
uaoieewqvaxcfy-uhfffaoysa-
2050-43-3
4-acetamido-m-xylene
MFCD00026125
2',4'-Dimethylacetanilide, 98%
NSC37567
2,4-Acetoxylidide
Acetanilide,4'-dimethyl-
WLN: 1VMR B1 D1
2,4-Dimethylacetanilide,98%
SCHEMBL2306741
CHEMBL3188564
2(2),4(2)-Dimethylacetanilide
CAA05043
Tox21_301646
CCG-52355
STK267008
AKOS000504351
AS-8580
N-(2,4-DIMETHYLPHENYL)ACETAMID
NCGC00256267-01
PD094265
SY005895
CAS-2050-43-3
DB-066224
CS-0038858
NS00026652
EN300-15543
W11349
SR-01000641596-1
Q27258029
Z27801599
N-(2,4-Dimethylphenyl)acetamide 100 microg/mL in Acetonitrile