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N-(2,5-dimethoxyphenyl)-2-iodo-acetamide

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Identification
Molecular formula
C10H12INO3
CAS number
60802-29-3
IUPAC name
N-(2,5-dimethoxyphenyl)-2-iodo-acetamide
State
State

This compound is generally in a solid state at room temperature. It is typically handled as a powder or crystalline substance.

Melting point (Celsius)
128.50
Melting point (Kelvin)
401.65
Boiling point (Celsius)
259.80
Boiling point (Kelvin)
532.95
General information
Molecular weight
335.11g/mol
Molar mass
335.1650g/mol
Density
1.8000g/cm3
Appearence

N-(2,5-dimethoxyphenyl)-2-iodo-acetamide typically appears as a crystalline solid that can range in color from white to off-white. This compound may also appear slightly beige due to impurities or degradation.

Comment on solubility

Solubility of N-(2,5-dimethoxyphenyl)-2-iodo-acetamide

N-(2,5-dimethoxyphenyl)-2-iodo-acetamide exhibits distinct solubility characteristics that are influenced by its chemical structure. Understanding the solubility of this compound is pivotal for its applications in various fields.

Solubility in Different Solvents

This compound is generally soluble in organic solvents while displaying limited solubility in water. Here are some key points regarding its solubility:

  • Organic Solvents: Soluble in solvents like ethanol, methanol, and chloroform.
  • Water: Exhibits low solubility, which is typical for compounds containing aromatic rings and halogens.
  • Polarity: The presence of methoxy groups enhances solubility in polar organic solvents but can limit interaction with water.

Factors Affecting Solubility

The solubility of N-(2,5-dimethoxyphenyl)-2-iodo-acetamide can be affected by various factors:

  1. Temperature: An increase in temperature usually enhances solubility.
  2. pH Levels: The acid-base nature of the solvent can influence the extent to which the compound dissolves.
  3. Presence of Other Compounds: Solubility can change in mixtures with other chemicals or solvents.

In conclusion, the solubility of N-(2,5-dimethoxyphenyl)-2-iodo-acetamide has practical implications for its usability in formulations, as it affects bioavailability and chemical reactivity. Its limited water solubility suggests that careful consideration must be taken when designing experiments or processes involving this compound.

Interesting facts

Interesting Facts about N-(2,5-dimethoxyphenyl)-2-iodo-acetamide

N-(2,5-dimethoxyphenyl)-2-iodo-acetamide is a fascinating chemical compound with unique properties and diverse applications. Here are some intriguing aspects of this compound:

  • Pharmaceutical Relevance: This compound has garnered attention in medicinal chemistry due to its potential pharmacological activities. Analogous compounds are often studied for their abilities to interact with biological targets, which can lead to the development of novel therapeutic agents.
  • Structural Highlights: The presence of the 2,5-dimethoxyphenyl group contributes to the compound's lipophilicity, enhancing its ability to cross cellular membranes. This structural feature is crucial for the bioactivity of many compounds.
  • Halogen Chemistry: The inclusion of the iodine atom introduces interesting aspects of reactivity. Halogenated compounds often exhibit unique chemical behaviors, paving the way for various substitution reactions.
  • Application in Synthesis: N-(2,5-dimethoxyphenyl)-2-iodo-acetamide can act as a versatile building block in organic synthesis. Its reactive functional groups make it an excellent candidate for further derivatization, allowing chemists to explore a myriad of chemical pathways.
  • Research Potential: Given its structural complexity, this compound can serve as a model for understanding the interactions between different substituents and their effects on reactivity and biological activity, making it a target for further research in organic and medicinal chemistry.

In conclusion, N-(2,5-dimethoxyphenyl)-2-iodo-acetamide exemplifies the intricate relationship between structure and function in chemistry. Its unique characteristics allow for a wide range of applications, pushing the boundaries of what we know in both synthetic and medicinal realms.

Synonyms
N-(2,5-dimethoxyphenyl)-2-iodoacetamide
ACETANILIDE, 2',5'-DIMETHOXY-2-IODO-
26958-85-0
XK09DLU2AU
Acetamide, N-(2,5-dimethoxyphenyl)-2-iodo-
NSC 226371
BRN 2730175
UNII-XK09DLU2AU
NSC-226371
DTXSID40181443
RefChem:161531
DTXCID50103934
Acetamide, N-(2,5-dimethoxyphenyl)-2-iodo-(9CI)
632-753-1
2',5'-Dimethoxy-2-iodoacetanilide
NSC226371
WLN: I1VMR BO1 EO1
SCHEMBL20189628
SCHEMBL30593409
Acetanilide,5'-dimethoxy-2-iodo-
Acetamide,5-dimethoxyphenyl)-2-iodo-
AKOS024406587