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N'-(2,5-dimethoxyphenyl)pyridine-4-carboxamidine

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Identification
Molecular formula
C14H15N3O2
CAS number
486-89-5
IUPAC name
N'-(2,5-dimethoxyphenyl)pyridine-4-carboxamidine
State
State

At room temperature, N'-(2,5-dimethoxyphenyl)pyridine-4-carboxamidine is typically in a solid state. It is stable under normal conditions and should be handled with care to maintain its structural integrity.

Melting point (Celsius)
184.00
Melting point (Kelvin)
457.00
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.00
General information
Molecular weight
286.14g/mol
Molar mass
286.1250g/mol
Density
1.2500g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It is commonly used in research and is characterized by its aromatic structure, which includes a dimethoxyphenyl group attached to a pyridine ring.

Comment on solubility

Solubility of N'-(2,5-dimethoxyphenyl)pyridine-4-carboxamidine

N'-(2,5-dimethoxyphenyl)pyridine-4-carboxamidine is an intriguing compound when it comes to its solubility characteristics. The solubility of this compound can be influenced by various factors:

  • Polarity: The presence of both the pyridine group and the amidine functional group contributes to its polar nature, which could promote solubility in polar solvents.
  • Hydrogen Bonding: The ability of the amidine group to engage in hydrogen bonding may enhance solubility in protic solvents, such as water or alcohols.
  • Alkyl Substituents: The dimethoxy groups on the phenyl ring can affect solubility due to their electron-donating effects, potentially increasing solubility in organic solvents.

In general, one might expect the compound to display increased solubility in:

  1. Polar solvents (e.g., ethanol, methanol)
  2. Protic solvents due to hydrogen bonding
  3. Organic solvents such as dichloromethane or ethyl acetate

However, definitive solubility data may vary depending on specific conditions like temperature and concentration and should be investigated experimentally. As always, it’s critical to consult reliable sources or conduct practical tests for the most accurate assessment of solubility characteristics.

Interesting facts

Interesting Facts about N'-(2,5-Dimethoxyphenyl)pyridine-4-carboxamidine

N'-(2,5-Dimethoxyphenyl)pyridine-4-carboxamidine is an intriguing compound that has captured the attention of researchers due to its unique structure and potential applications. Here are some fascinating details:

  • Structure and Functionality: The compound features a pyridine ring, which is well-known for its role in various biological activities. The substitution of the phenyl group with methoxy groups enhances its lipophilicity, allowing it to traverse biological membranes more effectively.
  • Biological Activity: Research indicates that derivatives of carboxamidine compounds have been studied for their potential in medicinal chemistry. They may exhibit antimicrobial, anticancer, and anti-inflammatory properties, making them valuable candidates for drug development.
  • Medicinal Chemistry: The amidine group in the compound has been associated with various pharmacological effects. The ability to modify and synthesize different derivatives opens up numerous avenues in treatment strategies for diseases.
  • Synthetic Versatility: The synthesis of this compound can be achieved through several methods, often involving the coupling of pyridine derivatives with substituted phenols. This diversity in synthesis allows chemists to tailor properties that can lead to novel compounds.
  • Potential in Material Science: Beyond its biological implications, compounds like N'-(2,5-Dimethoxyphenyl)pyridine-4-carboxamidine can play important roles in the field of materials science, particularly in the development of organic electronic devices due to their electronic properties.

In summary, N'-(2,5-Dimethoxyphenyl)pyridine-4-carboxamidine is not just a compound of interest for its chemical composition but is a potential player in the advancement of both medicinal and materials chemistry. Its exploration may lead to innovative solutions in healthcare and technology.

Synonyms
N-(2,5-Dimethoxyphenyl)isonicotinamidine
23564-31-0
BRN 0486039
ISONICOTINAMIDINE, N-(2,5-DIMETHOXYPHENYL)-
4-Pyridinecarboximidamide, N-(2,5-dimethoxyphenyl)-
DTXSID50178162
RefChem:349653
DTXCID80100653